OncoProt

You want to:

Build an exploratory oncological proteomic analysis project
Analyser le protéome d’une structure subcellulaire, de cellules ou fraction tissulaire
Identify new biomarkers for diagnosis, prognosis or to predict response to treatment
Quantify a biomarker of interest
Create a proteomics database
Perform tissue proteomic profiling analysis
Benefit from a bioinformatics processing service, support for the graphic representation and interpretation of proteomics data

Learn more

OncoProt

Platform services

Design concept
analytic

Sample preparation (cutting – microdissection)

Proteomic analysis by mass spectrometry

Treatment of
raw data,
statistical analysis

Graphic representation, integrative analysis, support for interpretation

Prices: Quote on request

The Oncoprot platform offers to combine laser microdissection and mass spectrometry to study the proteome of all types of oncological cellular or tissue structures

Microdissection makes it possible to isolate a particular population of cells or a cellular region of interest using laser cutting, from specimens fixed in formalin and embedded in paraffin.

The proteins are then extracted after reversal of the binding, and are analyzed by mass spectrometry to identify and quantify them. By proteomic profiling, we can use all the deregulated proteins as an identity card for a pathology, which makes it possible to define reference profiles with diagnostic, prognostic value or response to treatments.

Thanks to dedicated bioinformatics and integrative biology tools and the intervention of the bioinformatician of our team, we can be of support in the biological interpretation of proteomics data and in the graphical representation of your results.

Equipment

LEICA RM2255 automatic microtome (TBM Core Histopathology Platform)
PALM microbeam ZEISS microdissection device (Centre Magendie Bordeaux)
Fusion Lumos mass spectrometer (Bordeaux proteomics platform); a high-resolution mass spectrometer dedicated to the activity is being acquired