2026

Genevois C, Dugot-Senant N, Canron MH, Azzi-Martin L, Grenier N, Couillaud F, Mazzocco C. Bevacizumab-IRDye800 as an imaging probe for the detection of prostate cancer in mice. Sci Rep. 2026 Mar 26. [PubMed] [Vivoptic] [Histopathologie]

Guecamburu M, Pavot A, Legrix A, Jeannière C, Belaroussi Y, Thumerel M, Samaniego E, Begueret H, Maucort G, Decoeur F, Dupuy JW, Raymond AA, Esteves P, Grassion L, Dournes G, Berger P, Maurat E, Raasch K, Latouille E, Studer V, Dupin I, Henrot P, Zysman M. A new tunable 3D alveolospheres model from human alveolar epithelial type 2 cells (AEC2) with reduced heterogeneity for studying cigarette smoke extract exposure. Respir Res. 2026 Mar 17. [PubMed] [OncoProt] [FACSility]

Di Tommaso S, Chauveau B, Dourthe C, Dupuy JW, Saltel F, Bail BL, Raymond AA. Quantitative enrichment of amyloid precursors refines mass spectrometry-based amyloidosis diagnosis. Clin Proteomics. 2026 Mar 17. [PubMed] [OncoProt] [Histopathologie]

Mahmoudi N, Lesieur R, Rey S, Paiva Dos Santos B, Catros S, Garbay B, Amedee Vilamitjana J, Roque M. A neurovascularized bone regeneration strategy for mandibular and alveolar bone defects based on elastin-like biomaterials. Regenerative Biomaterials. [Link] [Histopathologie]

Delobel V, Grenier C, Boulestreau R, Rubin S, Vaurs J, Jaspard-Vinassa B, Casas E, Busson M, Combrouze C, Proust C, Caro I, Morel JL, Bontempi B, Mishra A, Debette S, Duplàa C, Couffinhal T, Peghaire C. Endothelial TRIM47 regulates blood-brain barrier integrity and cognition via the KEAP1/NRF2 signalling pathway in mice. Commun Biol. 2026 Feb 10;9(1):399. [PubMed] [Vect’UB]

Galtier J, Peanne R, Le Morvan V, Blondy T, Melane M, Bidon A, Chopin A, Prochazkova-Carlotti M, Poglio S, Merlio JP, Chevret E, Gros A, Pham-Ledard A, Beylot-Barry M, Bresson-Bepoldin L. Cutaneous diffuse large B-cell lymphoma induces a macrophage immunosuppressive phenotype through IL-10 secretion. Blood Adv. 2026 Feb 10;10(3):850-863. [PubMed] [FACSility]

Bonnard B, Chatefau A, Dourthe C, Di Tommaso S, Dupuy JW, Mahouche I, Solorzano J, Le Bras M, Raymond AA, Moreau V, Jabouille A, Blangy A, Martineau Y, Saltel F. Src promotes tumor cell invasion by hijacking the translation machineries. Cell Rep. 2026 Feb 23;45(3):116989. [PubMed] [OncoProt]  [Vect’UB]

Khoubai FZ, Calovoulos A, Guillorit H, Carrillo-Reixach J, Del Rio-Alvarez A, Klein P, Coma MS, Avignon C, Rousseau B, Mora Charrot L, Fedou S, Dupuy JW, Royo L, Domingo-Sàbat M, Thézé N, Siegfried G, Khatib AM, Cairo S, Indersie E, Jain BP, Trézéguet V, Gontier E, Lamoureux F, Guettier C, Mussini C, Hagedorn M, Armengol C, Grosset CF. EZH2 is a key prognostic marker and therapeutic target in aggressive and proliferative hepatoblastoma. Mol Cancer. 2026 Feb 23. [PubMed] [Vect’UB]

Marsères G, Gentil C, Tinevez C, Courant M, Cosentino A, Cornillot-Clément S, Bigot V, Pitard V, Zouine A, Izotte J, Garrigue I, Prouzet-Mauleon V, Turcq B, Anglicheau D, Forcade E, Kaminski H, Silva-Santos B, Merville P, Capone M, Déchanet-Merville J, Couzi L. Adoptive γδ T cell therapy controls cytomegalovirus infection in preclinical transplantation models. Nat Commun. 2026 Feb 17. [PubMed] [FACSility] [CRISP’edit] [Vect’UB]

Uguen K, Bergot T, Scott-Boyer MP, Chapalain S, Desdouets C, Commet S, Zhu C, Xu Y, Wang Y, Roscioli T, Tran-Mau-Them F, Faivre L, Maraval J, Delanne J, Denommé-Pichon AS, Vitobello A, Jost C, Planes M, Hiatt S, Wheeler P, Gonzaga-Jauregui C, Wang H, Xin B, Sency V, Kruer MC, Bakhtiari S, Sulem P, Curry C, Prescott T, Strobl-Wildemann G, Brunet T, Doco Fenzy M, Courtin T, Poirsier C, Bjørg Hammer T, Fenger CD, MacPherson M, Izumi K, Leonard J, Li D, Zackai EH, Glass IA, Ward S, Campeau PM, Borroto MCH, Le Moigno L, Van Esch H, De Waele L, Calame DG, Lupski JR, Barcia G, Peduto C, Planté-Bordeneuve P, Dupuis L, Mendoza-Londono R, Stavropoulos DJ, Gillibert-Duplantier J, Besnard T, Do Souto Ferreira L, Cogné B, Bézieau S, Droit A, Corcos L, Lippert E, Férec C, Küry S, Bernard DG. De novo variants in the splicing factor gene SF3B1 are associated with neurodevelopmental disorders. Nat Commun. 2026 Jan 23. [PubMed] [Vect’UB]

Bouchez CL, Molinié T, Duranthon G, Lillo S, Pellon C, El Mammeri N, Dartigues B, Pasdois P, Pinson B, Nikolski M, Devin A, Mourier A, Ullrich RT, Daubon T. The Antiseizure Medication Stiripentol Inhibits Mitochondrial Complex I by Blocking Early-Stage Electron Transfer. J Biol Chem. 2026 Jan 20:111179. [PubMed] [SAM]

Freyermuth C, Dupuy JW, Renault TT, Claverol S, Raymond AA, Thinon E. A Chemical Proteomics Method to Quantify Cysteine S-Acylation. ACS Chem Biol. 2026 Jan 13. [PubMed] [OncoProt]

Boutin J, Fayet S, Marin V, Bergès C, Riandière M, Toutain J, Lamrissi-Garcia I, Thibault C, Cappellen D, Dabernat S, Poulet A, Francillette M, Droin N, Debeissat C, Brunet de la Grange P, Moreau-Gaudry F, Bedel A. Single-cell multiplex approaches deeply map ON-target CRISPR-genotoxicity and reveal its mitigation by palbociclib and long-term engraftment. Nat Commun. 2026 Jan 10. [PubMed] [FACSility]

2025

Migayron L, Merhi R, Avril C, Léonard S, Zouine A, Jouenne F, Gilardeau S, Drullion C, Thiolat D, Mertinaj E, Humeau M, Mauroux A, Guégan JP, Gauthereau X, Mourah S, Darde T, Bordes S, Closs-Gonthier B, Seneschal J, Boniface K. Immune control of functional memory CD8 T cells in normal-appearing vitiligo skin. Sci Adv. 2025 Dec 12;11(50):eadu9360. [PubMed] [FACSility] [OneCell]

Rouyer L, Normand L, Richard E, Allain N, Giraud J, Di-Tommaso S, Dourthe C, Raymond AA, Dupuy JW, Moreau K, Iggo R, MacGrogan G, Dugot-Senant N, Bouter A, Tan S, Favereaux A, Moreau V, Luco RF, Ros M, Saltel F. Cancer cells transfer invasive properties through microRNAs contained in collagen tracks. Cell Rep. 2025 Dec 10;44(12):116725. [Pubmed] [OncoProt] [Histopathologie] [Vect’UB] [CRISP’edit]

Leon C, Odou MF, Roquelaure B, Lebreton L, Ruiz M, Schneider CV, Renoux C, Evrard A, Balduyck M, Dechomet M, Lombard C, Butori-Pepino M, Schneider KM, Marin V, di-Tomasso S, Dourthe C, Dupuy JW, Raymond AA, Collardeau-Frachon S, Haffner A, Fritih R, Goubert E, Geromel V, Joly P, Fabre A, Bouchecareilh M. Characterization of a novel SERPINA1 variant carrying two missense mutations: molecular mechanisms and functional impact. Orphanet J Rare Dis. 2025 Nov 21. [PubMed] [OncoProt]

Doisy M, Gaci A, Soukarieh O, Proust C, Trégouët DA, Goyenvalle A. Targeting a Pathogenic Variant Creating an Upstream AUG in the ENG 5′ Untranslated Region with Antisense Oligonucleotides Fails to Restore Protein Expression. Nucleic Acid Ther. 2025 Nov 17. [PubMed] [Vect’UB]

Autaa G, Korenkov D, van Beek J, Pellegrin I, Parfait B, van Baarle D, Launay O, Tartour E, Appay V. Re-evaluating CD57 as a marker of T cell senescence: implications for immune ageing and differentiation. Immun Ageing. 2025 Oct 31;22(1):47. [PubMed] [FACSility]

Leiva S, Freyermuth C, Claverol S, Mantione D, Thinon E. Affinity-based protein profiling of the antiviral natural product nanchangmycin. RSC Chem Biol. 2026, Advance Article. [Link] [UB’L3]

Kervella M, Bertile F, Granger-Farbos A, Pinson B, Villette C, Heintz D, Schmitt A, Quque M, Bouillaud F, Criscuolo F. Inter-Caste Comparison Reveals a Unique Bioenergetic Signature in Long-Lived Ant Queens. Mol Ecol. 2025 Oct 10:e70127. [PubMed] [SAM]

Lehmann A, Karatas E, Leon C, Di Tommaso S, Dourthe C, Dupuy JW, Raymond AA, Collardeau-Frachon S, Bouchecareilh M. Alpha-1 Antitrypsin–Mediated Liver Disease: A Role for the NRF1–Proteasome Axis? Liver international Communications. 2025 Sep, Volume 6, issue 3. [Link] [Vect’UB] [OncoProt]

Ralph de Oliveira IL, da Silva Moura JA, Recordon-Pinson P, Lagadec F, da Rosa MM, Gonçalves SMC, Viana DCF, de Moraes Gomes PAT, da Rocha Pitta MG, de Melo Rêgo MJB, Pereira MC, Métifiot M, Andreola ML, da Rocha Pitta MG. Novel Thiazolidinedione Derivatives as Potential ZIKV Antiviral Inhibitors. Microorganisms. 2025 Aug 22;13(9):1967. [PubMed] [UB’L3]

Sequera C, Grattarola M, Cannet F, Dobric A, Michea Veloso P, Methia M, Richelme S, El Kaoutari A, Kousteridou P, Debayle D, Kübler L, Nuciforo S, Boursier Y, Dupont M, Pizzimenti S, Barrera G, Dupuy JW, Saltel F, Heim MH, Vasseur S, Adhoute X, Guillaumond F, Borg JP, Morel C, Maina F. The HDAC inhibitor romidepsin renders liver cancer vulnerable to RTK targeting and immunologically active. Nat Commun. 2025 Aug 25;16(1):7919. [PubMed] [OncoProt]

Marichez A, Raymond AA, Saltel F, Chiche L. ASO Author’s Reflections: Extrahepatic Cholangiocarcinoma as an Oncological Consistent Entity: Insights from Proteomic Profiling and Lack of Anatomical Impact. Ann Surg Oncol. 2025 Aug 13. [PubMed] [OncoProt]

Isnard A, Cramier LA, Vergara R, Boubaddi M, Fouche D, Fernandez B, Senant N, Denost Q, Rullier É, Dubus P, Dabernat S, Dupin C, Vendrely V, Rullier A, Amintas S. Association Between CD147 Expression, RAS Mutational Status, and Local Recurrence in Resected Locally Advanced Rectal Cancer. Cancer Med. 2025 Aug;14(15):e71087. [PubMed] [Histopathologie]

Normand L, Bonnard B, Sala M, Di Tommaso S, Dourthe C, Raymond AA, Dupuy JW, Mercier L, Goetz JG, Moreau V, Henriet E, Saltel F. Tks5 interactome reveals endoplasmic-reticulum-associated translation machinery in invadosomes. FEBS J. 2025 Jul 24. [PubMed] [OncoProt] [FACSility]

Meynard T, Royer F, Houssier R, Bajeux O, Paget S, Lahdaoui F, Mogrovejo Valdivia A, Maubon N, Vicogne J, Van Seuningen I, Senez V. Fabrication of a bioreactor combining soft lithography and vat photopolymerisation to study tissues and multicellular organisms under dynamic culture conditions. Lab Chip. 2025 Jul 16. [PubMed] [Vect’UB]

Klein P, Guillorit H, Mora Charrot L, Laborde R, Dugot-Senant N, Izotte J, Rousseau B, Grosset CF. Design of a neonatal orthotopic metastatic xenograft model of hepatoblastoma in mice. Oncology. 2025 Jul 18:1-21. [PubMed] [Histopathologie]

Marichez A, Raymond AA, Boubaddi M, Toussaint N, Le Bail B, Belleannée G, Di Tommaso S, Dupuy JW, Dourthe C, Decraecker M, Saltel F, Laurent C, Chiche L. Blurring the Anatomical Lines in Extrahepatic Cholangiocarcinoma: An Integrated Clinic-Oncological and Exploratory Proteomic Comparison of Perihilar and Distal Tumors. Ann Surg Oncol. 2025 Jul 16. [PubMed] [OncoProt]

Nguyen HO, Pinson PR, Andreola ML, Papagno L, Appay V. Human Type-I Interferon Omega Holds Potent Antiviral Properties and Promotes Cytolytic CD8+ T Cell Responses. Eur J Immunol. 2025 Jul;55(7):e70003. [PubMed] [UB’L3] [FACSility]

Gabinaud E, Hannouche L, Veneziano-Broccia M, Van Agthoven J, Suffit J, Maurizio J, Potier D, Payet-Bornet D, Bastelica D, Andersen E, Ibrahim-Kosta M, Bigot T, Falaise C, Vincenot A, Morange PE, Saultier P, Alessi MC, Poggi M, Of Lille HU. FLI1 and GATA1 govern TLN1 transcription: new insights into FLI1-related platelet disorders. Haematologica. 2025 Jul 1;110(7):1584-1595. [PubMed] [Vect’UB]

Dousset L, Khalife F, Chalopin-Fillot D, Dartigues B, Naji F, Mahfouf W, Muzotte E, Rousseau B, Amoedo N, Claverol S, Bondaz M, Beltzung F, Jullie ML, Vergier B, Taieb A, Favot-Laforge L, Rossignol R, Beylot-Barry M, Nikolski M, Revani HR. Metabolism-based scoring of cutaneous squamous cell carcinoma to predict tumor features and responses to treatment by DHODH inhibitors. Br J Dermatol. 2025 Jun 27:ljaf253. [PubMed] [Vect’UB]

Chaillot L, Blondot ML, Recordon-Pinson P, Pellegrin I, Boizard-Moracchini A, Sliusar M, Leboucq T, Pujol N, Andreola ML, Bonnet F, Recher G, Andrique L, Nassoy P, Mathivet T, Bikfalvi A. CXCL10-dependent epithelial-vascular cross-talk for endothelial activation following SARS-CoV-2 infection. Sci Rep. 2025 Jul 1;15(1):21129. [PubMed] [VoxCell] [UB’L3]

Ferret L, Pol JG, Sauvat A, Stoll G, Alvarez-Valadez K, Muller A, Le Naour J, Peyre F, Anagnostopoulos G, Martins I, Maiuri MC, Wodrich H, Guittat L, Mergny JL, Kroemer G, Djavaheri-Mergny M. Lysosomal membrane permeabilization enhances the anticancer effects of POLR1 (RNA polymerase I) transcription inhibitors. Autophagy. 2025 Jun 18:1-20. [PubMed] [CRISP’edit]

Emanuelli A, Souleyreau W, Chouleur T, Boeckx B, Pobiedonoscew Y, Cooley L, Derieppe MA, Martineau J, Ambrosetti D, Bernhard JC, Sawai CM, Lambrechts D, Mathivet T, Bikfalvi A. Targeting the IL34-CSF1R axis improves metastatic renal cell carcinoma therapy outcome via immune-vascular crosstalk regulation. iScience. 2025 May 26;28(6):112752. [PubMed] [OneCell] [Vect’UB]

Lerouley O, Larrieu I, Ducrocq TL, Pinson B, Giraud MF, Mourier A. An alternative mechanism by which If1 prevents ATP hydrolysis by the ATP synthase subcomplex in S. cerevisiae. EMBO Rep. 2025 Jun 9. [PubMed] [SAM]

Plazolles N, Kulyk H, Cahoreau E, Biran M, Wargnies M, Pineda E, El Kadri M, Rimoldi A, Hervé P, Asencio C, Rivière L, Michels PAM, Inaoka D, Tétaud E, Portais JC, Bringaud F. The glycosomal ATP-dependent phosphofructokinase of Trypanosoma brucei operates also in the gluconeogenic direction. PLoS Biol. 2025 May 16;23(5):e3002938. [PubMed] [FACSility]

Ley-Ngardigal S, Claverol S, Sobilo L, Moreau M, Hubert C, Goupil J, Poulignon A, Mahfouf W, Fatrouni H, Dard L, Juan M, Gales L, Merched A, Tokarski C, Leblanc E, Galinier A, Lacombe D, Rezvani HR, Bellvert F, Pays K, Nizard C, Amoedo ND, Bulteau AL, Rossignol R. Repression of oxidative phosphorylation by NR2F2, MTERF3 and GDF15 in human skin under high-glucose stress. Redox Biol. 2025 May;82:103613. [PubMed] [CRISP’edit] [Vect’UB]

Alvarez-Valadez K, Sauvat A, Diharce J, Leduc M, Stoll G, Guittat L, Lambertucci F, Paillet J, Motiño O, Ferret L, Muller A, Forveille S, Maiuri MC, Kepp O, de Brevern AG, Wodrich H, Pol JG, Kroemer G, Djavaheri-Mergny M. Lysosomal damage due to cholesterol accumulation triggers immunogenic cell death. Autophagy. 2025 May;21(5):934-956. [PubMed] [CRISP’edit]

Celle E, Chahin A, Beaufils F, Cardouat G, Eyraud E, Bouchet C, Campagnac M, Ousova O, Begueret H, Thumerel M, Dubois R, Dupuy JW, Leste-Lasserre T, Lacomme S, Lager-Lachaud N, Bellvert F, Marthan R, Girodet PO, Berger P, Trian T, Esteves P. Bronchial smooth muscle extracellular vesicles interfere with bronchial epithelium metabolism and function in asthma. iScience. 2025 Apr 29;28(6):112546. [PubMed] [OncoProt]

Blanco-Domínguez R, Barros L, Carreira M, van der Ploeg M, Condeço C, Marsères G, Ferreira C, Costa C, Ferreira CM, Déchanet-Merville J, de Miranda NFCC, Mensurado S, Silva-Santos B. Dual modulation of cytotoxic and checkpoint receptors tunes the efficacy of adoptive Delta One T cell therapy against colorectal cancer. Nat Cancer. 2025 Apr 16. [PubMed] [CRISP’edit]

Dupin I, Henrot P, Maurat E, Abohalaka R, Chaigne S, El Hamrani D, Eyraud E, Prevel R, Esteves P, Campagnac M, Dubreuil M, Cardouat G, Bouchet C, Ousova O, Dupuy JW, Trian T, Thumerel M, Begueret H, Girodet PO, Marthan R, Zysman M, Freund-Michel V, Berger P. CXCR4 Blockade Alleviates Pulmonary and Cardiac Outcomes in Early COPD. Am J Respir Cell Mol Biol. 2025 Apr 8. [PubMed] [OncoProt] [FACSility]

Morel CA, Asencio C, Moreira D, Blancard C, Salin B, Gontier E, Duvezin-Caubet S, Rojo M, Bringaud F, Tetaud E. A new member of the dynamin superfamily modulates mitochondrial membrane branching in Trypanosoma brucei. Curr Biol. 2025 Mar 6:S0960-9822(25)00196-4. [PubMed] [FACSility]

Lesbats J, Brillac A, Reisz JA, Mukherjee P, Lhuissier C, Fernández-Monreal M, Dupuy JW, Sequeira A, Tioli G, De La Calle Arregui C, Pinson B, Wendisch D, Rousseau B, Efeyan A, Sander LE, D’Alessandro A, Garaude J. Macrophages recycle phagocytosed bacteria to fuel immunometabolic responses. Nature. 2025 Feb 26. [PubMed] [OncoProt] [SAM] [FACSility] [OneCell]

Stoppin-Mellet V, Serre L, Arnal I. Tubulin-GDP: an unexpected player in microtubule stabilization. Med Sci (Paris). 2025 Feb;41(2):125-127. [PubMed] [SAM]

Burban A, Tessier C, Larroquette M, Guyon J, Lubiato C, Pinglaut M, Toujas M, Galvis J, Dartigues B, Georget E, Luchman HA, Weiss S, Cappellen D, Nicot N, Klink B, Nikolski M, Brisson L, Mathivet T, Bikfalvi A, Daubon T, Sharanek A. Exploiting metabolic vulnerability in glioblastoma using a brain-penetrant drug with a safe profile. EMBO Mol Med. 2025 Feb 3. [PubMed] [FACSility]

Demoures B, Soulet F, Descarpentrie J, Galeano-Otero I, Sanchez Collado J, Casado M, Smani T, González A, Alves I, Lalloué F, Masri B, Rascol E, Dupuy JW, Dourthe C, Saltel F, Raymond AA, Badiola I, Evrard S, Villoutreix B, Pernot S, Siegfried G, Khatib AM. Repression of apelin Furin cleavage sites provides antimetastatic strategy in colorectal cancer. EMBO Mol Med. 2025 Feb 17. [PubMed] [OncoProt] [Vect’UB] [OneCell]

Le Nihouannen D, Boiziau C, Rey S, Agadzhanian N, Dusserre N, Cordelières F, Priault M, Boeuf H. Inhibiting Autophagy by Chemicals During SCAPs Osteodifferentiation Elicits Disorganized Mineralization, While the Knock-Out of Atg57 Genes Leads to Cell Adaptation. Cells. 2025 Jan 20;14(2):146. [PubMed] [Vect’UB]

Autaa G, Papagno L, Nogimori T, Boizard-Moracchini A, Korenkov D, Roy M, Suzuki K, Masuta Y, White E, Llewellyn-Lacey S, Yoshioka Y, Nicoli F, Price DA, Dechanet-Merville J, Yamamoto T, Pellegrin I, Appay V. Ageing and inflammation limit the induction of SARS-CoV-2-specific CD8+ T cell responses in severe COVID-19. JCI Insight. 2025 Jan 23:e180867. [PubMed] [FACSility]

Cullot G, Lagarde V, Cayuela JM, Prouzet-Mauléon V, Turcq B, Hicheri Y, Roy L, Braun T, Mozziconacci MJ, Alary AS, Dulucq S. Asciminib resistance of a new BCR::ABL1 p.I293_K294insSSLRD mutant detected in a Ph + ALL patient. Ann Hematol. 2025 Jan 7. [PubMed] [FACSility] [CRISP’edit]

Spivak I, Guldiken N, Usachov V, Schaap F, Damink SWMO, Bouchecareilh M, Lehmann A, Fu L, Mo FR, Ensari GK, Hufnagel F, Fromme M, Preisinger C, Strnad P. Alpha-1 Antitrypsin Inclusions Sequester GRP78 in a Bile Acid-Inducible Manner. Liver Int. 2025 Jan;45(1):e16207. [PubMed] [OncoProt]

2024

Hammad N, Ransy C, Pinson B, Talmasson J, Bréchot C, Rossignol JF, Bouillaud F. Nitazoxanide controls virus viability through its impact on membrane bioenergetics. Sci Rep. 2024 Dec 28;14(1):30679. [PubMed] [SAM]

Dousset L, Mahfouf W, Younes H, Fatrouni H, Faucheux C, Muzotte E, Khalife F, Rossignol R, Moisan F, Cario M, Claverol S, Favot-Laforge L, Nieminen AI, Vainio S, Ali N, Rezvani HR. Energy metabolism rewiring following acute UVB irradiation is largely dependent on nuclear DNA damage. Free Radic Biol Med. 2024 Dec 10;227:459-471. [PubMed] [Vect’UB]

Mattuizzi A, Sauvestre F, Fargeix T, White E, Leibler C, Cargou M, Dugot-Senant N, Douchet I, Duluc D, Bordes C, Truchetet MÉ, Richez C, Forcade É, Duffau P, Viallard JF, Sentilhes L, Blanco P, Lazaro E. Inflammasome-targeted therapy might prevent adverse perinatal outcomes of recurrent chronic intervillositis of unknown etiology. Nat Commun. 2024 Oct 30;15(1):9396. [PubMed] [Histopathologie]

Amintas S, Cullot G, Boubaddi M, Rébillard J, Karembe L, Turcq B, Prouzet-Mauléon V, Bedel A, Moreau-Gaudry F, Cappellen D, Dabernat S. Integrating allele-specific PCR with CRISPR-Cas13a for sensitive KRAS mutation detection in pancreatic cancer. J Biol Eng. 2024 Oct 1;18(1):53. [PubMed] [CRISP’edit]

White E, Papagno L, Samri A, Sugata K, Hejblum B, Henry AR, Rogan DC, Darko S, Recordon-Pinson P, Dudoit Y, Llewellyn-Lacey S, Chakrabarti LA, Buseyne F, Migueles SA, Price DA, Andreola MA, Satou Y, Thiebaut R, Katlama C, Autran B, Douek DC, Appay V. Clonal succession after prolonged antiretroviral therapy rejuvenates CD8+ T cell responses against HIV-1. Nat Immunol. 2024 Sep;25(9):1555-1564. [PubMed] [FACSility]

Saha O, Melo de Farias AR, Pelletier A, Siedlecki-Wullich D, Landeira BS, Gadaut J, Carrier A, Vreulx AC, Guyot K, Shen Y, Bonnefond A, Amouyel P, Tcw J, Kilinc D, Queiroz CM, Delahaye F, Lambert JC, Costa MR. The Alzheimer’s disease risk gene BIN1 regulates activity-dependent gene expression in human-induced glutamatergic neurons. Mol Psychiatry. 2024 Sep;29(9):2634-2646. [PubMed] [Vect’UB]

Bioulac-Sage P, Sempoux C, Gouw ASH, Paradis V, Le Bail B, Raymond AA, Balabaud C. Clinical relevance of subtyping CTNNB1-mutated hepatocellular adenomas: Different risk patterns according to the mutation type. Liver international Communications. 2024 Sep, Volume 5, issue 3. [Link] [OncoProt]

Desigaux T, Comperat L, Dusserre N, Stachowicz ML, Lea M, Dupuy JW, Vial A, Molinari M, Fricain JC, Paris F, Oliveira H. 3D bioprinted breast cancer model reveals stroma-mediated modulation of extracellular matrix and radiosensitivity. Bioact Mater. 2024 Sep 5;42:316-327. [PubMed] [OncoProt]

Maurat E, Raasch K, Leipold AM, Henrot P, Zysman M, Prevel R, Trian T, Krammer T, Bergeron V, Thumerel M, Nassoy P, Berger P, Saliba AE, Andrique L, Recher G, Dupin I. A novel in vitro tubular model to recapitulate features of distal airways: The bronchioid. Eur Respir J. 2024 Sep 4:2400562. [PubMed] [VoxCell] [FACSility] [OneCell]

Jeanpierre M, Cognard J, Tusseau M, Riller Q, Bui LC, Berthelet J, Laurent A, Crickx E, Parlato M, Stolzenberg MC, Suarez F, Leverger G, Aladjidi N, Collardeau-Frachon S, Pietrement C, Malphettes M, Froissart A, Bole-Feysot C, Cagnard N, Rodrigues Lima F, Walzer T, Rieux-Laucat F, Belot A, Mathieu AL. Haploinsufficiency in PTPN2 leads to early-onset systemic autoimmunity from Evans syndrome to lupus. J Exp Med. 2024 Sep 2;221(9):e20232337. [PubMed] [Vect’UB]

Bessières B, Dupuis J, Groc L, Bontempi B, Nicole O. Synaptic rearrangement of NMDA receptors controls memory engram formation and malleability in the cortex. Sci Adv. 2024 Aug 30;10(35):eado1148. [PubMed] [Vect’UB]

Pouxvielh K, Marotel M, Drouillard A, Villard M, Moreews M, Bossan A, Poiget M, Khoryati L, Benezech S, Fallone L, Hamada S, Rousseaux N, Picq L, Rocca Y, Berton A, Teixeira M, Mathieu AL, Ainouze M, Hasan U, Fournier A, Thaunat O, Marçais A, Walzer T. Tumor-induced natural killer cell dysfunction is a rapid and reversible process uncoupled from the expression of immune checkpoints. Sci Adv. 2024 Aug 30;10(35):eadn0164. [PubMed] [Vect’UB]

Nokin MJ, Darbo E, Richard E, San José S, de Hita S, Prouzet-Mauleon V, Turcq B, Gerardelli L, Crake R, Velasco V, Koopmansch B, Lambert F, Xue JY, Sang B, Horne J, Ziemons E, Villanueva A, Blomme A, Herfs M, Cataldo D, Calvayrac O, Porporato P, Nadal E, Lito P, Jänne PA, Ricciuti B, Awad MM, Ambrogio C, Santamaría D; Bolero Consortium. In vivo vulnerabilities to GPX4 and HDAC inhibitors in drug-persistent versus drug-resistant BRAFV600E lung adenocarcinoma. Cell Rep Med. 2024 Aug 20;5(8):101663. [PubMed] [CRISP’edit] [Vect’UB]

Bagdadi N, Wu J, Delaroche J, Serre L, Delphin C, De Andrade M, Carcel M, Nawabi H, Pinson B, Vérin C, Couté Y, Gory-Fauré S, Andrieux A, Stoppin-Mellet V, Arnal I. Stable GDP-tubulin islands rescue dynamic microtubules. J Cell Biol. 2024 Aug 5;223(8):e202307074. [PubMed] [SAM]

Refeyton A, Labat V, Mombled M, Vlaski-Lafarge M, Ivanovic Z. Functional single-cell analyses of mesenchymal stromal cell proliferation and differentiation using ALDH-activity and mitochondrial ROS content. Cytotherapy. 2024 Aug;26(8):813-824. [PubMed] [FACSility]

Sikora J, Dovero S, Kinet R, Arotcarena ML, Bohic S, Bezard E, Fernagut PO, Dehay B. Nigral ATP13A2 depletion induces Parkinson’s disease-related neurodegeneration in a pilot study in non-human primates. NPJ Parkinsons Dis. 2024 Aug 1;10(1):141. [PubMed] [Vect’UB]

Jamet Z, Mergaux C, Meras M, Bouchet D, Villega F, Kreye J, Prüss H, Groc L. NMDA receptor autoantibodies primarily impair the extrasynaptic compartment. Brain. 2024 Aug 1;147(8):2745-2760. [PubMed] [FACSility]

Guyon J, Haidar Ahmad S, El Baba R, Le Quang M, Bikfalvi A, Daubon T, Herbein G. Generation of glioblastoma in mice engrafted with human cytomegalovirus-infected astrocytes. Cancer Gene Ther. 2024 Jul;31(7):1070-1080. [PubMed] [Histopathologie]

Dantzer C, Vaché J, Brunel A, Mahouche I, Raymond AA, Dupuy JW, Petrel M, Bioulac-Sage P, Perrais D, Dugot-Senant N, Verdier M, Bessette B, Billottet C, Moreau V. Emerging role of oncogenic ß-catenin in exosome biogenesis as a driver of immune escape in hepatocellular carcinoma. Elife. 2024 Jul 15;13:RP95191. [PubMed] [OncoProt] [Histopathologie] [FACSility] [OneCell]

Loret C, Pauset A, Faye PA, Prouzet-Mauleon V, Pyromali I, Nizou A, Miressi F, Sturtz F, Favreau F, Turcq B, Lia AS. CRISPR Base Editing to Create Potential Charcot-Marie-Tooth Disease Models with High Editing Efficiency: Human Induced Pluripotent Stem Cell Harboring SH3TC2 Variants. Biomedicines. 2024 Jul 12;12(7):1550. [PubMed] [CRISP’edit]

Benavides-Nieto M, Adam F, Martin E, Boussard C, Lagresle-Peyrou C, Callebaut I, Kauskot A, Repérant C, Feng M, Bordet JC, Castelle M, Morelle G, Brouzes C, Zarhrate M, Panikulam P, Lambert N, Picard C, Bodet D, Rouger-Gaudichon J, Revy P, de Villartay JP, Moshous D. Somatic RAP1B gain-of-function variant underlies isolated thrombocytopenia and immunodeficiency. J Clin Invest. 2024 Jul 11;134(17):e169994. [PubMed] [Vect’UB]

Singh M, Roubertie F, Ozturk C, Borchiellini P, Rames A, Bonnemain J, Gollob SD, Wang SX, Naulin J, El Hamrani D, Dugot-Senant N, Gosselin I, Grenet C, L’Heureux N, Roche ET, Kawecki F. Hemodynamic evaluation of biomaterial-based surgery for Tetralogy of Fallot using a biorobotic heart, in silico, and ovine models. Sci Transl Med. 2024 Jul 10;16(755):eadk2936. [PubMed] [Histopathologie]

Yared N, Papadopoulou M, Barennes P, Pham HP, Quiniou V, Netzer S, Kaminski H, Burguet L, Demeste A, Colas P, Mora-Charrot L, Rousseau B, Izotte J, Zouine A, Gauthereau X, Vermijlen D, Déchanet-Merville J, Capone M. Long-lived central memory γδ T cells confer protection against murine cytomegalovirus reinfection. PLoS Pathog. 2024 Jul 8;20(7):e1010785. [PubMed] [FACSility] [OneCell]

Azzi-Martin L, Touffait-Calvez V, Everaert M, Jia R, Sifré E, Seeneevassen L, Varon C, Dubus P, Ménard A. Cytolethal Distending Toxin Modulates Cell Differentiation and Elicits Epithelial to Mesenchymal Transition. J Infect Dis. 2024 Jun 14;229(6):1688-1701. [PubMed] [VoxCell]

Garreau A, Santa P, Dubois M, Brisou D, Levionnois É, Laurent P, Ferriere A, Roubertie A, Loizon S, Duluc D, Blanco P, Contin-Bordes C, Truchetet ME, Sisirak V. The deficiency of DNASE1L3 does not affect systemic sclerosis pathogenesis in two inducible murine models of the disease. Eur J Immunol. 2024 Jun;54(6):e2350903. [PubMed] [FACSility] [OneCell]

Asencio C, Hervé P, Morand P, Oliveres Q, Morel CA, Prouzet-Mauleon V, Biran M, Monic S, Bonhivers M, Robinson DR, Ouellette M, Rivière L, Bringaud F, Tetaud E. Streptococcus pyogenes Cas9 ribonucleoprotein delivery for efficient, rapid and marker-free gene editing in Trypanosoma and Leishmania. Mol Microbiol. 2024 Jun;121(6):1079-1094. [PubMed] [CRISP’edit] [FACSility]

Scuvée D, Goñi-Urriza M, Tessier E, Gassie C, Ranchou-Peyruse M, Amouroux D, Guyoneaud R, Khalfaoui-Hassani B. Molybdate inhibits mercury methylation capacity of Pseudodesulfovibrio hydrargyri BerOc1 regardless of the growth metabolism. Environ Sci Pollut Res Int. 2024 Jun;31(30):42686-42697. [PubMed] [FACSility]

Puginier E, Leal-Fischer K, Gaitan J, Lallouet M, Scotti PA, Raoux M, Lang J. Extracellular electrophysiology on clonal human β-cell spheroids. Front Endocrinol (Lausanne). 2024 May 31;15:1402880. [PubMed] [Vect’UB]

Lee A, Simon AA, Boyreau A, Allain-Courtois N, Lambert B, Pradère JP, Saltel F, Cognet L. Identification of Early Stage Liver Fibrosis by Modifications in the Interstitial Space Diffusive Microenvironment Using Fluorescent Single-Walled Carbon Nanotubes. Nano Lett. 2024 May 8;24(18):5603-5609. [PubMed] [Histopathologie]

Mazzocco C, Genevois C, Li Q, Doudnikoff E, Dutheil N, Leste-Lasserre T, Arotcarena ML, Bezard E. In vivo bioluminescence imaging of the intracerebral fibroin-controlled AAV-α-synuclein diffusion for monitoring the central nervous system and peripheral expression. Sci Rep. 2024 Apr 27;14(1):9710. [PubMed] [Vivoptic]

Domblides C, Crampton S, Liu H, Bartleson JM, Nguyen A, Champagne C, Landy EE, Spiker L, Proffitt C, Bhattarai S, Grawe AP, Fuentealba Valenzuela M, Lartigue L, Mahouche I, Dupaul-Chicoine J, Nishimura K, Lefort F, Decraecker M, Velasco V, Netzer S, Pitard V, Roy C, Soubeyran I, Racine V, Blanco P, Déchanet-Merville J, Saleh M, Canna SW, Furman D, Faustin B. Human NLRC4 expression promotes cancer survival and associates with type I interferon signaling and immune infiltration. J Clin Invest. 2024 Apr 23;134(11):e166085. [PubMed] [FACSility]

Vélez EJ, Schnebert S, Goguet M, Balbuena-Pecino S, Dias K, Beauclair L, Fontagné-Dicharry S, Véron V, Depincé A, Beaumatin F, Herpin A, Seiliez I. Chaperone-mediated autophagy protects against hyperglycemic stress. Autophagy. 2024 Apr;20(4):752-768. [PubMed] [FACSility]

Zaafour A, Seeneevassen L, Nguyen TL, Genevois C, Nicolas N, Sifré E, Giese A, Porcheron C, Descarpentrie J, Dubus P, Khatib AM, Varon C. Inhibition of proprotein convertases activity results in repressed stemness and invasiveness of cancer stem cells in gastric cancer. Gastric Cancer. 2024 Mar;27(2):292-307. [PubMed] [Vivoptic]

Seeneevassen L, Zaafour A, Sifré E, Genevois C, Nguyen TL, Pobiedonoscew Y, Giese A, Guignard J, Tiffon C, Rousseau B, Raymond AA, Belleannée G, Boeuf H, Gronnier C, Martin OCB, Giraud J, Lehours P, Dubus P, Varon C. Targeting metastasis-initiating cancer stem cells in gastric cancer with leukaemia inhibitory factor. Cell Death Discov. 2024 Mar 7;10(1):120. [PubMed] [OncoProt] [Vivoptic] [OneCell] [Vect’UB] [FACSility]

Garcia G, Labrouche-Colomer S, Duvignaud A, Clequin E, Dussiau C, Trégouët DA, Malvy D, Prevel R, Zouine A, Pellegrin I, Goret J, Mamani-Matsuda M, Dewitte A, James C. Impaired balance between neutrophil extracellular trap formation and degradation by DNases in COVID-19 disease. J Transl Med. 2024 Mar 7;22(1):246. [PubMed] [FACSility]

Giraud J, Chalopin D, Ramel E, Boyer T, Zouine A, Derieppe MA, Larmonier N, Adotevi O, Le Bail B, Blanc JF, Laurent C, Chiche L, Derive M, Nikolski M, Saleh M. THBS1+ myeloid cells expand in SLD hepatocellular carcinoma and contribute to immunosuppression and unfavorable prognosis through TREM1. Cell Rep. 2024 Feb 27;43(2):113773. [PubMed] [CRISP’edit] [FACSility] [OneCell] [Histopathologie]

Bertillot F, Andrique L, Ureña Martin C, Zajac O, de Plater L, Norton MM, Richard A, Alessandri K, Gurchenkov BG, Fage F, Asnacios A, Lamaze C, Das M, Maître JL, Nassoy P, Matic Vignjevic D. Compressive stress triggers fibroblasts spreading over cancer cells to generate carcinoma in situ organization. Commun Biol. 2024 Feb 15;7(1):184. [PubMed] [VoxCell]

Boutin J, Genevois C, Couillaud F, Lamrissi-Garcia I, Guyonnet-Duperat V, Bibeyran A, Lalanne M, Amintas S, Moranvillier I, Richard E, Blouin JM, Dabernat S, Moreau-Gaudry F, Bedel A. CRISPR editing to mimic porphyria combined with light: A new preclinical approach for prostate cancer. Mol Ther Oncol. 2024 Feb 8;32(1):200772. [PubMed] [Vect’UB] [Vivoptic]

Grindel AL, Fretellier N, Soares M, Bouzakher N, Millot Maysounabe V, Santus R, Bawa O, Wintrebert M, Couquelet C, Robert P, Emile JF, Capron C. Antitumoral effect of local injection of TLR-9 agonist emulsified in Lipiodol with systemic anti-PD-1 in a murine model of colorectal carcinoma. Front Immunol. 2024 Jan 16;14:1272246. [PubMed] [Vivoptic]

Basbous S, Dif L, Dantzer C, Di-Tommaso S, Dupuy JW, Bioulac-Sage P, Raymond AA, Desdouets C, Saltel F, Moreau V. Loss of RND3/RHOE controls entosis through LAMP1 expression in hepatocellular carcinoma. Cell Death Dis. 2024 Jan 13;15(1):46. [PubMed] [OncoProt]

Guy A, Garcia G, Gourdou-Latyszenok V, Wolff-Trombini L, Josserand L, Kimmerlin Q, Favre S, Kilani B, Marty C, Boulaftali Y, Labrouche-Colomer S, Mansier O, James C. Platelets and neutrophils cooperate to induce increased neutrophil extracellular trap formation in JAK2V617F myeloproliferative neoplasms. J Thromb Haemost. 2024 Jan;22(1):172-187. [PubMed] [FACSility]

2023

Gounou C, Rouyer L, Siegfried G, Harté E, Bouvet F, d’Agata L, Darbo E, Lefeuvre M, Derieppe MA, Bouton L, Mélane M, Chapeau D, Martineau J, Prouzet-Mauleon V, Tan S, Souleyreau W, Saltel F, Argoul F, Khatib AM, Brisson AR, Iggo R, Bouter A. Inhibition of the membrane repair protein annexin-A2 prevents tumor invasion and metastasis. Cell Mol Life Sci. 2023 Dec 13;81(1):7. [PubMed] [CRISP’edit]

Park DS, Kozaki T, Tiwari SK, Moreira M, Khalilnezhad A, Torta F, Olivié N, Thiam CH, Liani O, Silvin A, Phoo WW, Gao L, Triebl A, Tham WK, Gonçalves L, Kong WT, Raman S, Zhang XM, Dunsmore G, Dutertre CA, Lee S, Ong JM, Balachander A, Khalilnezhad S, Lum J, Duan K, Lim ZM, Tan L, Low I, Utami KH, Yeo XY, Di Tommaso S, Dupuy JW, Varga B, Karadottir RT, Madathummal MC, Bonne I, Malleret B, Binte ZY, Wei Da N, Tan Y, Wong WJ, Zhang J, Chen J, Sobota RM, Howland SW, Ng LG, Saltel F, Castel D, Grill J, Minard V, Albani S, Chan JKY, Thion MS, Jung SY, Wenk MR, Pouladi MA, Pasqualini C, Angeli V, Cexus ONF, Ginhoux F. iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer. Nature. 2023 Nov;623(7986):397-405. [PubMed] [OncoProt]

Soukarieh O, Tillet E, Proust C, Dupont C, Jaspard-Vinassa B, Soubrier F, Goyenvalle A, Eyries M, Trégouët DA. uAUG creating variants in the 5’UTR of ENG causing Hereditary Hemorrhagic Telangiectasia. NPJ Genom Med. 2023 Oct 17;8(1):32. [PubMed] [Vect’UB]

Boileau C, Deforges S, Peret A, Scavarda D, Bartolomei F, Giles A, Partouche N, Gautron J, Viotti J, Janowitz H, Penchet G, Marchal C, Lagarde S, Trebuchon A, Villeneuve N, Rumi J, Marissal T, Khazipov R, Khalilov I, Martineau F, Maréchal M, Lepine A, Milh M, Figarella-Branger D, Dougy E, Tong S, Appay R, Baudouin S, Mercer A, Smith JB, Danos O, Porter R, Mulle C, Crépel V. GluK2 Is a Target for Gene Therapy in Drug-Resistant Temporal Lobe Epilepsy. Ann Neurol. 2023 Oct;94(4):745-761. [PubMed] [Vect’UB]

Di Tommaso S, Dourthe C, Dupuy JW, Dugot-Senant N, Cappellen D, Cazier H, Paradis V, Blanc JF, Le Bail B, Balabaud C, Bioulac-Sage P, Saltel F, Raymond AA. Spatial characterisation of β-catenin-mutated hepatocellular adenoma subtypes by proteomic profiling of the tumour rim. JHEP Rep. 2023 Sep 22;6(2):100913. [PubMed] [OncoProt] [Histopathologie]

Nguyen Ky M, Duran A, Hasantari I, Bru A, Deloire M, Brochet B, Ruet A, Schmitt N. Natalizumab Treatment Induces Proinflammatory CD4 T Cells Preferentially in the Integrin β7+ Compartment. Neurol Neuroimmunol Neuroinflamm. 2023 Sep 22;10(6):e200166. [PubMed] [FACSility]

Pinson B, Moenner M, Saint-Marc C, Granger-Farbos A, Daignan-Fornier B. On-demand utilization of phosphoribosyl pyrophosphate by downstream anabolic pathways. J Biol Chem. 2023 Aug;299(8):105011. [PubMed] [SAM] [Vect’UB]

Cullot G, Boutin J, Fayet S, Prat F, Rosier J, Cappellen D, Lamrissi I, Pennamen P, Bouron J, Amintas S, Thibault C, Moranvillier I, Laharanne E, Merlio JP, Guyonnet-Duperat V, Blouin JM, Richard E, Dabernat S, Moreau-Gaudry F, Bedel A. Cell cycle arrest and p53 prevent ON-target megabase-scale rearrangements induced by CRISPR-Cas9. Nat Commun. 2023 Jul 10;14(1):4072. [PubMed] [Vect’UB]

Lavie J, Lalou C, Mahfouf W, Dupuy JW, Lacaule A, Cywinska AA, Lacombe D, Duchêne AM, Raymond AA, Rezvani HR, Ngondo RP, Bénard G. The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins. Cell Rep. 2023 Jun 27;42(6):112579. [PubMed] [OncoProt] [CRISP’edit]

Guerville F, Vialemaringe M, Cognet C, Duffau P, Lazaro E, Cazanave C, Bonnet F, Leleux O, Rossignol R, Pinson B, Tumiotto C, Gabriel F, Appay V, Déchanet-Merville J, Wittkop L, Faustin B, Pellegrin I; on the behalf of ANRS CO3 Aquitaine / AquiVIH-NA study group. Mechanisms of systemic low-grade inflammation in HIV patients on long-term suppressive antiretroviral therapy: the inflammasome hypothesis. AIDS. 2023 Jun 1;37(7):1035-1046. [PubMed] [SAM]

Gounou C, Bouvet F, Liet B, Prouzet-Mauléon V, d’Agata L, Harté E, Argoul F, Siegfried G, Iggo R, Khatib AM, Bouter A. Annexin-A5 and annexin-A6 silencing prevents metastasis of breast cancer cells in zebrafish. Biol Cell. 2023 Jun;115(6):e202200110. [PubMed] [CRISP’edit] [Vect’UB]

Jang G, Contreras Castillo S, Esteva E, Upadhaya S, Feng J, Adams NM, Richard E, Awatramani R, Sawai CM, Reizis B. Stem cell decoupling underlies impaired lymphoid development during aging. Proc Natl Acad Sci U S A. 2023 May 30;120(22):e2302019120. [PubMed] [OneCell]

Cullot G, Amintas S, Karembé L, Prouzet-Mauléon V, Rébillard J, Boureau L, Cappellen D, Bedel A, Moreau-Gaudry F, Dulucq S, Dabernat S, Turcq B. Specific High-Sensitivity Enzymatic Reporter UnLOCKing-Mediated Detection of Oncogenic BCR::ABL1 and EGFR Rearrangements. CRISPR J. 2023 Apr;6(2):140-151. [PubMed] [CRISP’edit] [FACSility]

Cohen PJR, Luquet E, Pletenka J, Leonard A, Warter E, Gurchenkov B, Carrere J, Rieu C, Hardouin J, Moncaubeig F, Lanero M, Quelennec E, Wurtz H, Jamet E, Demarco M, Banal C, Van Liedekerke P, Nassoy P, Feyeux M, Lefort N, Alessandri K. Engineering 3D micro-compartments for highly efficient and scale-independent expansion of human pluripotent stem cells in bioreactors. Biomaterials. 2023 Apr;295:122033. [PubMed] [FACSility]

Giraud J, Seeneevassen L, Rousseau B, Bouriez D, Sifré E, Giese A, Nguyen TL, Tiffon C, Lippi Y, Azzi-Martin L, Pannequin J, Ménard A, Bessède E, Staedel C, Mégraud F, Belleannée G, Lehours P, Gronnier C, Dubus P, Varon C. CD44v3 is a marker of invasive cancer stem cells driving metastasis in gastric carcinoma. Gastric Cancer. 2023 Mar;26(2):234-249. [PubMed] [FACSility]

Le Saos-Patrinos C, Loizon S, Zouine A, Turpin D, Dilhuydy MS, Blanco P, Sisirak V, Forcade E, Duluc D. Elevated levels of circulatory follicular T helper cells in chronic lymphocytic leukemia contribute to B cell expansion. J Leukoc Biol. 2023 Mar 1;113(3):305-314. [PubMed] [FACSility]

Curcio A, Perez JE, Prévéral S, Fromain A, Genevois C, Michel A, Van de Walle A, Lalatonne Y, Faivre D, Ménager C, Wilhelm C. The role of tumor model in magnetic targeting of magnetosomes and ultramagnetic liposomes. Sci Rep. 2023 Feb 8;13(1):2278. [PubMed] [Vivoptic]

Abou-Hamdan M, Saleh R, Mani S, Dournaud P, Metifiot M, Blondot ML, Andreola ML, Abdel-Sater F, De Reggi M, Gressens P, Laforge M. Potential antiviral effects of pantethine against SARS-CoV-2. Sci Rep. 2023 Feb 8;13(1):2237. [PubMed] [UB’L3]

Ropio J, Prochazkova-Carlotti M, Batista R, Pestana A, Chebly A, Ferrer J, Idrissi Y, Cappellen D, Durães C, Boaventura P, Vinagre J, Azzi-Martin L, Poglio S, Cabeçadas J, Campos MA, Beylot-Barry M, Sobrinho-Simões M, Merlio JP, Soares P, Chevret E. Spotlight on hTERT Complex Regulation in Cutaneous T-Cell Lymphomas. Genes (Basel). 2023 Feb 8;14(2):439. [PubMed] [FACSility] [Vect’UB]

Arricau-Bouvery N, Dubrana MP, Canuto F, Duret S, Brocard L, Claverol S, Malembic-Maher S, Foissac X. Flavescence dorée phytoplasma enters insect cells by a clathrin-mediated endocytosis allowing infection of its insect vector. Sci Rep. 2023 Feb 7;13(1):2211. [PubMed] [FACSility]

Leclerc D, Goujon L, Jaillard S, Nouyou B, Cluzeau L, Damaj L, Dubourg C, Etcheverry A, Levade T, Froissart R, Dréano S, Guillory X, Eriksson LA, Launay E, Mouriaux F, Belaud-Rotureau MA, Odent S, Gilot D. Gene Editing Corrects In Vitro a G > A GLB1 Transition from a GM1 Gangliosidosis Patient. CRISPR J. 2023 Feb;6(1):17-31. [PubMed] [CRISP’edit]

Prochazkova-Carlotti M, Gros A, Richard E, Cherrier F, Laharanne E, Idrissi Y, Baron C, Poglio S, Ducharme O, Menguy S, Pham-Ledard A, Beylot-Barry M, Merlio JP, Bresson-Bepoldin L. Patient-Derived Xenograft and Cell Line Models of Human Primary Cutaneous Diffuse Large B-Cell Lymphoma-Leg Type. J Invest Dermatol. 2023 Feb;143(2):340-344.e6. [PubMed] [FACSility]

Gest C, Sena S, Dif L, Neaud V, Loesch R, Dugot-Senant N, Paysan L, Piquet L, Robbe T, Allain N, Dembele D, Guettier C, Bioulac-Sage P, Rullier A, Le Bail B, Grosset CF, Saltel F, Lagrée V, Colnot S, Moreau V. Antagonism between wild-type and mutant β-catenin controls hepatoblastoma differentiation via fascin-1. JHEP Rep. 2023 Feb 1;5(5):100691. [PubMed] [Histopathologie]

Barrouilhet S, Monperrus M, Tessier E, Khalfaoui-Hassani B, Guyoneaud R, Isaure MP, Goñi-Urriza M. Effect of exogenous and endogenous sulfide on the production and the export of methylmercury by sulfate-reducing bacteria. Environ Sci Pollut Res Int. 2023 Jan;30(2):3835-3846. [PubMed] [FACSility]

Fregona V, Bayet M, Bouttier M, Largeaud L, Hamelle C, Jamrog LA, Prade N, Lagarde S, Hebrard S, Luquet I, Mansat-De Mas V, Nolla M, Pasquet M, Didier C, Khamlichi AA, Broccardo C, Delabesse É, Mancini SJC, Gerby B. Stem cell-like reprogramming is required for leukemia-initiating activity in B-ALL. J Exp Med. 2024 Jan 1;221(1):e20230279. [PubMed] [Vect’UB]

Santa P, Roubertie A, Loizon S, Garreau A, Ferriere A, Duluc D, Sisirak V. Enrichment of Large Numbers of Splenic Mouse Dendritic Cells After Injection of Flt3L-Producing Tumor Cells. Methods Mol Biol. 2023;2618:173-186. [PubMed] [FACSility]

2022

Alannan M, Fatrouni H, Trézéguet V, Dittrich-Domergue F, Moreau P, Siegfried G, Liet B, Khatib AM, Grosset CF, Badran B, Fayyad-Kazan H, Merched AJ. Targeting PCSK9 in Liver Cancer Cells Triggers Metabolic Exhaustion and Cell Death by Ferroptosis. Cells. 2022 Dec 23;12(1):62. [PubMed] [Vect’UB] [Histopathologie]

Alannan M, Trézéguet V, Amoêdo ND, Rossignol R, Mahfouf W, Rezvani HR, Dittrich-Domergue F, Moreau P, Lacomme S, Gontier E, Grosset CF, Badran B, Fayyad-Kazan H, Merched AJ. Rewiring Lipid Metabolism by Targeting PCSK9 and HMGCR to Treat Liver Cancer. Cancers (Basel). 2022 Dec 20;15(1):3. [PubMed] [Vect’UB]

Peru S, Prochazkova-Carlotti M, Cherrier F, Velazquez J, Richard E, Idrissi Y, Cappellen D, Azzi-Martin L, Pham-Ledard A, Beylot-Barry M, Merlio JP, Poglio S. Cutaneous Lymphocyte Antigen Is a Potential Therapeutic Target in Cutaneous T-Cell Lymphoma. J Invest Dermatol. 2022 Dec;142(12):3243-3252.e10. [PubMed] [FACSility] [Vect’UB]

Amintas S, Beaumont P, Dupin C, Moranvillier I, Lamrissi I, Patel E, Fernandez B, Bibeyran A, Boutin J, Richard T, Krisa S, Moreau-Gaudry F, Bedel A, Cappellen D, Pinson B, Vendrely V, Dabernat S. Differential Uridyl-diphosphate-Glucuronosyl Transferase 1A enzymatic arsenal explains the specific cytotoxicity of resveratrol towards tumor colorectal cells. J Funct Foods. 2022 Dec;99:105345. [Link] [Vect’UB] [SAM]

Amrane S, Jaubert C, Bedrat A, Rundstadler T, Recordon-Pinson P, Aknin C, Guédin A, De Rache A, Bartolucci L, Diene I, Lemoine F, Gascuel O, Pratviel G, Mergny JL, Andreola ML. Deciphering RNA G-quadruplex function during the early steps of HIV-1 infection. Nucleic Acids Res. 2022 Nov 28;50(21):12328-12343. [PubMed] [UB’L3]

Chauveau B, Garric A, Di Tommaso S, Raymond AA, Visentin J, Vermorel A, Dugot-Senant N, Déchanet-Merville J, Duong Van Huyen JP, Rabant M, Couzi L, Saltel F, Merville P. WARS1, TYMP and GBP1 display a distinctive microcirculation pattern by immunohistochemistry during antibody-mediated rejection in kidney transplantation. Sci Rep. 2022 Nov 9;12(1):19094. [PubMed] [OncoProt] [Histopathologie]

Gaillard M, Parlanti E, Sourzac M, Couillaud F, Genevois C, Boutry S, Rigaud C, Daverat F. New insights into detecting alizarin from autofluorescence in marked glass eels. Sci Rep. 2022 Sep 26;12(1):15985. [PubMed] [Vivoptic]

Bacon S, Seeneevassen L, Fratacci A, Rose F, Tiffon C, Sifré E, Haykal MM, Moubarak MM, Ducournau A, Bruhl L, Claverol S, Tokarski C, Gouloumi AR, Pateras IS, Daubon T, Lehours P, Varon C, Martin OCB. Nrf2 Downregulation Contributes to Epithelial-to-Mesenchymal Transition in Helicobacter pylori-Infected Cells. Cancers (Basel). 2022 Sep 2;14(17):4316. [PubMed] [CRISP’edit] [FACSility]

Lapaillerie D, Charlier C, Guyonnet-Dupérat V, Murigneux E, Fernandes HS, Martins FG, Magalhães RP, Vieira TF, Richetta C, Subra F, Lebourgeois S, Charpentier C, Descamps D, Visseaux B, Weigel P, Favereaux A, Beauvineau C, Buron F, Teulade-Fichou MP, Routier S, Gallois-Montbrun S, Meertens L, Delelis O, Sousa SF, Parissi V. Selection of Bis-Indolyl Pyridines and Triphenylamines as New Inhibitors of SARS-CoV-2 Cellular Entry by Modulating the Spike Protein/ACE2 Interfaces. Antimicrob Agents Chemother. 2022 Aug 16;66(8):e0008322. [PubMed] [Vect’UB]

Larrieu CM, Storevik S, Guyon J, Pagano Zottola AC, Bouchez CL, Derieppe MA, Tan TZ, Miletic H, Lorens J, Tronstad KJ, Daubon T, Røsland GV. Refining the Role of Pyruvate Dehydrogenase Kinases in Glioblastoma Development. Cancers (Basel). 2022 Aug 2;14(15):3769. [PubMed] [CellOxia] [Histopathologie]

Sannino A, Scarfì MR, Dufossée M, Romeo S, Poeta L, Prouzet-Mauléon V, Priault M, Zeni O. Inhibition of Autophagy Negates Radiofrequency-Induced Adaptive Response in SH-SY5Y Neuroblastoma Cells. Int J Mol Sci. 2022 Jul 29;23(15):8414. [PubMed] [CRISP’edit] [FACSility] [Vect’UB]

Beucher G, Blondot ML, Celle A, Pied N, Recordon-Pinson P, Esteves P, Faure M, Métifiot M, Lacomme S, Dacheux D, Robinson DR, Längst G, Beaufils F, Lafon ME, Berger P, Landry M, Malvy D, Trian T, Andreola ML, Wodrich H. Bronchial epithelia from adults and children: SARS-CoV-2 spread via syncytia formation and type III interferon infectivity restriction. Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2202370119. [PubMed] [UB’L3]

Celle A, Esteves P, Cardouat G, Beaufils F, Eyraud E, Dupin I, Maurat E, Lacomme S, Ousova O, Begueret H, Thumerel M, Marthan R, Girodet PO, Berger P, Trian T. Rhinovirus infection of bronchial epithelium induces specific bronchial smooth muscle cell migration of severe asthmatic patients. J Allergy Clin Immunol. 2022 Jul;150(1):104-113. [PubMed] [FACSility]

Tingaud-Sequeira A, Mercier E, Michaud V, Pinson B, Gazova I, Gontier E, Decoeur F, McKie L, Jackson IJ, Arveiler B, Javerzat S. The Dct-/- Mouse Model to Unravel Retinogenesis Misregulation in Patients with Albinism. Genes (Basel). 2022 Jun 27;13(7):1164. [PubMed] [SAM]

Paget-Blanc V, Pfeffer ME, Pronot M, Lapios P, Angelo MF, Walle R, Cordelières FP, Levet F, Claverol S, Lacomme S, Petrel M, Martin C, Pitard V, De Smedt Peyrusse V, Biederer T, Perrais D, Trifilieff P, Herzog E. A synaptomic analysis reveals dopamine hub synapses in the mouse striatum. Nat Commun. 2022 Jun 3;13(1):3102. [PubMed] [FACSility]

Abelanet A, Camoin M, Rubin S, Bougaran P, Delobel V, Pernot M, Forfar I, Guilbeau-Frugier C, Galès C, Bats ML, Renault MA, Dufourcq P, Couffinhal T, Duplàa C. Increased Capillary Permeability in Heart Induces Diastolic Dysfunction Independently of Inflammation, Fibrosis, or Cardiomyocyte Dysfunction. Arterioscler Thromb Vasc Biol. 2022 Jun;42(6):745-763. [PubMed] [FACSility]

Chebly A, Ropio J, Peloponese JM, Poglio S, Prochazkova-Carlotti M, Cherrier F, Ferrer J, Idrissi Y, Segal-Bendirdjian E, Chouery E, Farra C, Pham-Ledard A, Beylot-Barry M, Merlio JP, Tomb R, Chevret E. Exploring hTERT promoter methylation in cutaneous T-cell lymphomas. Mol Oncol. 2022 May;16(9):1931-1946. [PubMed] [FACSility]

Basbous S, Paysan L, Sena S, Allain N, Hiriart JB, Dugot-Senant N, Rousseau B, Chevret E, Lagrée V, Moreau V. Silencing of RND3/RHOE inhibits the growth of human hepatocellular carcinoma and is associated with reversible senescence. Cancer Gene Ther. 2022 May;29(5):437-444. [PubMed] [Histopathologie] [Vect’UB] [FACSility]

Dard L, Hubert C, Esteves P, Blanchard W, Bou About G, Baldasseroni L, Dumon E, Angelini C, Delourme M, Guyonnet-Dupérat V, Claverol S, Fontenille L, Kissa K, Séguéla PE, Thambo JB, Nicolas L, Herault Y, Bellance N, Dias Amoedo N, Magdinier F, Sorg T, Lacombe D, Rossignol R. HRAS germline mutations impair LKB1/AMPK signaling and mitochondrial homeostasis in Costello syndrome models. J Clin Invest. 2022 Apr 15;132(8):e131053. [PubMed] [Vect’UB]

Labat V, Bayard ENVTD, Refeyton A, Huart M, Avalon M, Debeissat C, Rodriguez L, de la Grange PB, Ivanovic Z, Vlaski-Lafarge M. Regulatory Crosstalk between Physiological Low O2 Concentration and Notch Pathway in Early Erythropoiesis. Biomolecules. 2022 Apr 2;12(4):540. [PubMed] [FACSility] [Vect’UB]

Sala M, Allain N, Moreau M, Jabouille A, Henriet E, Abou-Hammoud A, Uguen A, Di-Tommaso S, Dourthe C, Raymond AA, Dupuy JW, Gerard E, Dugot-Senant N, Rousseau B, Merlio JP, Pham-Ledart A, Vergier B, Tartare-Deckert S, Moreau V, Saltel F. Discoidin Domain Receptor 2 orchestrates melanoma resistance combining phenotype switching and proliferation. Oncogene. 2022 Apr;41(18):2571-2586. [PubMed] [OncoProt] [Histopathologie]

Debeissat C, Avalon M, Huart M, Duchez P, Rodriguez L, Vlaski-Lafarge M, Ivanovic Z, Brunet de la Grange P. Alpha Lipoic-Acid Potentiates Ex Vivo Expansion of Human Steady-State Peripheral Blood Hematopoietic Primitive Cells. Biomolecules. 2022 Mar 11;12(3):431. [PubMed] [FACSility]

Rahal F, Capdevielle C, Rousseau B, Izotte J, Dupuy JW, Cappellen D, Chotard G, Ménard M, Charpentier J, Jecko V, Caumont C, Gimbert E, Grosset CF, Hagedorn M. An EZH2 blocker sensitizes histone mutated diffuse midline glioma to cholesterol metabolism inhibitors through an off-target effect. Neurooncol Adv. 2022 Mar 1;4(1):vdac018. [PubMed] [Vect’UB]

Chauveau B, Raymond AA, Di Tommaso S, Visentin J, Vermorel A, Dugot-Senant N, Dourthe C, Dupuy JW, Déchanet-Merville J, Duong Van Huyen JP, Rabant M, Couzi L, Saltel F, Merville P. The Proteome of Antibody-Mediated Rejection: From Glomerulitis to Transplant Glomerulopathy. Biomedicines. 2022 Feb 28;10(3):569. [PubMed] [OncoProt] [Histopathologie]

Badon A, Andrique L, Mombereau A, Rivet L, Boyreau A, Nassoy P, Recher G. The Incubascope: a simple, compact and large field of view microscope for long-term imaging inside an incubator. R Soc Open Sci. 2022 Feb 9;9(2):211444. [PubMed] [VoxCell]

Jeanjean P, El Hamrani D, Genevois C, Quesson B, Couillaud F. Combination of MRI-Guided High-Intensity Focused Ultrasound and Bioluminescent Biological Systems to Assess Thermal Therapies for Tumor and Tumor Microenvironment. Advanced Materials Technologies. 2022 Jan24 ;7,7. [Link] [Vivoptic]

Dupont M, Huart M, Lauvinerie C, Bidet A, Guitart AV, Villacreces A, Vigon I, Desplat V, El Habhab A, Pigneux A, Ivanovic Z, Brunet De la Grange P, Dumas PY, Pasquet JM. Autophagy Targeting and Hematological Mobilization in FLT3-ITD Acute Myeloid Leukemia Decrease Repopulating Capacity and Relapse by Inducing Apoptosis of Committed Leukemic Cells. Cancers (Basel). 2022 Jan 17;14(2):453. [PubMed] [Vect’UB] [CellOxia] [FACSility]

Hobson BD, Kong L, Angelo MF, Lieberman OJ, Mosharov EV, Herzog E, Sulzer D, Sims PA. Subcellular and regional localization of mRNA translation in midbrain dopamine neurons. Cell Rep. 2022 Jan 11;38(2):110208. [PubMed] [FACSility]

Lambert E, Saha O, Soares Landeira B, Melo de Farias AR, Hermant X, Carrier A, Pelletier A, Gadaut J, Davoine L, Dupont C, Amouyel P, Bonnefond A, Lafont F, Abdelfettah F, Verstreken P, Chapuis J, Barois N, Delahaye F, Dermaut B, Lambert JC, Costa MR, Dourlen P. The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects. Acta Neuropathol Commun. 2022 Jan 8;10(1):4. [PubMed] [Vect’UB]

Kaminski H, Marseres G, Yared N, Nokin MJ, Pitard V, Zouine A, Garrigue I, Loizon S, Capone M, Gauthereau X, Mamani-Matsuda M, Coueron R, Durán RV, Pinson B, Pellegrin I, Thiébaut R, Couzi L, Merville P, Déchanet-Merville J. mTOR Inhibitors Prevent CMV Infection through the Restoration of Functional αβ and γδ T cells in Kidney Transplantation. J Am Soc Nephrol. 2022 Jan;33(1):121-137. [PubMed] [SAM] [FACSility] [OneCell]

Recher G, Mombereau A, Boyreau A, Nassoy P, Andrique L. 3D Tumor organoid models produced by cellular capsules technology CCT. Bull Cancer. 2022 Jan;109(1):38-48. [PubMed] [VoxCell]

Orieux A, Brunier J, Rigothier C, Pinson B, Dabernat S, Bats ML. Plasma creatinine below limit of quantification in a patient with acute kidney injury. Clin Chim Acta. 2022 Jan 1;524:101-105. [PubMed] [SAM]

2021

Mosca N, Khoubai FZ, Fedou S, Carrillo-Reixach J, Caruso S, Del Rio-Alvarez A, Dubois E, Avignon C, Dugot-Senant N, Guettier C, Mussini C, Zucman-Rossi J, Armengol C, Thiébaud P, Veschambre P, Grosset CF. LIM Homeobox-2 Suppresses Hallmarks of Adult and Pediatric Liver Cancers by Inactivating MAPK/ERK and Wnt/Beta-Catenin Pathways. Liver Cancer. 2021 Dec 21;11(2):126-140. [PubMed] [Histopathologie] [Vect’UB]

Lamaison C, Latour S, Hélaine N, Le Morvan V, Saint-Vanne J, Mahouche I, Monvoisin C, Dussert C, Andrique L, Deleurme L, Dessauge E, Pangault C, Baulande S, Legoix P, Seffals M, Broca-Brisson L, Alessandri K, Carlotti M, Soubeyran P, Merlio JP, Mourcin F, Nassoy P, Recher G, Tarte K, Bresson-Bepoldin L. A novel 3D culture model recapitulates primary FL B-cell features and promotes their survival. Blood Adv. 2021 Dec 14;5(23):5372-5386. [PubMed] [VoxCell] [FACSility]

Quilgars C, Cazalets JR, Bertrand SS. Developmentally Regulated Modulation of Lumbar Motoneurons by Metabotropic Glutamate Receptors: A Cellular and Behavioral Analysis in Newborn Mice. Front Cell Neurosci. 2021 Dec 9;15:770250. [PubMed] [OneCell]

Henrot P, Beaufils F, Thumerel M, Eyraud E, Boudoussier A, Begueret H, Maurat E, Girodet PO, Marthan R, Berger P, Dupin I, Zysman M. Circulating fibrocytes as a new tool to predict lung cancer progression after surgery? Eur Respir J. 2021 Dec 9;58(6):2101221. [PubMed] [FACSility]

Laurent P, Allard B, Manicki P, Jolivel V, Levionnois E, Jeljeli M, Henrot P, Izotte J, Leleu D, Groppi A, Seneschal J, Constans J, Chizzolini C, Richez C, Duffau P, Lazaro E, Forcade E, Schaeverbeke T, Pradeu T, Batteux F, Blanco P, Contin-Bordes C, Truchetet ME. TGFβ promotes low IL10-producing ILC2 with profibrotic ability involved in skin fibrosis in systemic sclerosis. Ann Rheum Dis. 2021 Dec;80(12):1594-1603. [PubMed] [Histopathologie] [FACSility] [OneCell]

Esteves P, Blanc L, Celle A, Dupin I, Maurat E, Amoedo N, Cardouat G, Ousova O, Gales L, Bellvert F, Begueret H, Thumerel M, Dupuy JW, Desbenoit N, Marthan R, Girodet PO, Rossignol R, Berger P, Trian T. Crucial role of fatty acid oxidation in asthmatic bronchial smooth muscle remodelling. Eur Respir J. 2021 Nov 25;58(5):2004252. [PubMed] [FACSility]

Dumas PY, Villacreces A, Guitart AV, El-Habhab A, Massara L, Mansier O, Bidet A, Martineau D, Fernandez S, Leguay T, Pigneux A, Vigon I, Pasquet JM, Desplat V. Dual Inhibition of FLT3 and AXL by Gilteritinib Overcomes Hematopoietic Niche-Driven Resistance Mechanisms in FLT3-ITD Acute Myeloid Leukemia. Clin Cancer Res. 2021 Nov 1;27(21):6012-6025. [PubMed] [Vect’UB] [FACSility] [CellOxia]

Chambraud B, Daguinot C, Guillemeau K, Genet M, Dounane O, Meduri G, Poüs C, Baulieu EE, Giustiniani J. Decrease of neuronal FKBP4/FKBP52 modulates perinuclear lysosomal positioning and MAPT/Tau behavior during MAPT/Tau-induced proteotoxic stress. Autophagy. 2021 Nov;17(11):3491-3510. [PubMed] [Vect’UB]

Campion O, Thevenard Devy J, Billottet C, Schneider C, Etique N, Dupuy JW, Raymond AA, Boulagnon Rombi C, Meunier M, Djermoune EH, Lelièvre E, Wahart A, Bour C, Hachet C, Cairo S, Bikfalvi A, Dedieu S, Devy J. LRP-1 Matricellular Receptor Involvement in Triple Negative Breast Cancer Tumor Angiogenesis. Biomedicines. 2021 Oct 9;9(10):1430. [PubMed] [OncoProt]

Eysert F, Coulon A, Boscher E, Vreulx AC, Flaig A, Mendes T, Hughes S, Grenier-Boley B, Hanoulle X, Demiautte F, Bauer C, Marttinen M, Takalo M, Amouyel P, Desai S, Pike I, Hiltunen M, Chécler F, Farinelli M, Delay C, Malmanche N, Hébert SS, Dumont J, Kilinc D, Lambert JC, Chapuis J. Alzheimer’s genetic risk factor FERMT2 (Kindlin-2) controls axonal growth and synaptic plasticity in an APP-dependent manner. Mol Psychiatry. 2021 Oct;26(10):5592-5607. [PubMed] [Vect’UB]

Amendola M, Bedel A, Buj-Bello A, Carrara M, Concordet JP, Frati G, Gilot D, Giovannangeli C, Gutierrez-Guerrero A, Laurent M, Miccio A, Moreau-Gaudry F, Sourd C, Valton J, Verhoeyen E. Recent Progress in Genome Editing for Gene Therapy Applications: The French Perspective. Hum Gene Ther. 2021 Oct;32(19-20):1059-1075. [PubMed] [Vect’UB]

Dourthe C, Julien C, Di Tommaso S, Dupuy JW, Dugot-Senant N, Brochard A, Le Bail B, Blanc JF, Chiche L, Balabaud C, Bioulac-Sage P, Saltel F, Raymond AA. Proteomic Profiling of Hepatocellular Adenomas Paves the Way to Diagnostic and Prognostic Approaches. Hepatology. 2021 Sep;74(3):1595-1610. [PubMed] [OncoProt] [Histopathologie]

Bakr M, Jullié D, Krapivkina J, Paget-Blanc V, Bouit L, Petersen JD, Retailleau N, Breillat C, Herzog E, Choquet D, Perrais D. The vSNAREs VAMP2 and VAMP4 control recycling and intracellular sorting of post-synaptic receptors in neuronal dendrites. Cell Rep. 2021 Sep 7;36(10):109678. [PubMed] [Vect’UB]

Beaufils F, Esteves P, Enaud R, Germande O, Celle A, Marthan R, Trian T, Fayon M, Berger P. Mitochondria are involved in bronchial smooth muscle remodeling in severe preschool wheezers. J Allergy Clin Immunol. 2021 Aug;148(2):645-651.e11. [PubMed] [FACSility]

Boutin J, Rosier J, Cappellen D, Prat F, Toutain J, Pennamen P, Bouron J, Rooryck C, Merlio JP, Lamrissi-Garcia I, Cullot G, Amintas S, Guyonnet-Duperat V, Ged C, Blouin JM, Richard E, Dabernat S, Moreau-Gaudry F, Bedel A. CRISPR-Cas9 globin editing can induce megabase-scale copy-neutral losses of heterozygosity in hematopoietic cells. Nat Commun. 2021 Aug 13;12(1):4922. [PubMed] [Vect’UB] [FACSility]

Harly C, Joyce SP, Domblides C, Bachelet T, Pitard V, Mannat C, Pappalardo A, Couzi L, Netzer S, Massara L, Obre E, Hawchar O, Lartigue L, Claverol S, Cano C, Moreau JF, Mahouche I, Soubeyran I, Rossignol R, Viollet B, Willcox CR, Mohammed F, Willcox BE, Faustin B, Déchanet-Merville J. Human γδ T cell sensing of AMPK-dependent metabolic tumor reprogramming through TCR recognition of EphA2. Sci Immunol. 2021 Jul 30;6(61):eaba9010. [PubMed] [FACSility]

Scherlinger M, Guillotin V, Douchet I, Vacher P, Boizard-Moracchini A, Guegan JP, Garreau A, Merillon N, Vermorel A, Ribeiro E, Machelart I, Lazaro E, Couzi L, Duffau P, Barnetche T, Pellegrin JL, Viallard JF, Saleh M, Schaeverbeke T, Legembre P, Truchetet ME, Dumortier H, Contin-Bordes C, Sisirak V, Richez C, Blanco P. Selectins impair regulatory T cell function and contribute to systemic lupus erythematosus pathogenesis. Sci Transl Med. 2021 Jun 30;13(600):eabi4994. [PubMed] [FACSility] [OneCell]

Javary J, Allain N, Ezzoukhry Z, Di Tommaso S, Dupuy JW, Costet P, Dugot-Senant N, Saltel F, Moreau V, Dubus P, Benhamouche-Trouillet S. Reptin/RUVBL2 is required for hepatocyte proliferation in vivo, liver regeneration and homeostasis. Liver Int. 2021 Jun;41(6):1423-1429. [PubMed] [OncoProt] [Histopathologie]

Poglio S, Prochazkova-Carlotti M, Cherrier F, Gros A, Laharanne E, Pham-Ledard A, Beylot-Barry M, Merlio JP. Xenograft and cell culture models of Sézary syndrome reveal cell of origin diversity and subclonal heterogeneity. Leukemia. 2021 Jun;35(6):1696-1709. [PubMed] [FACSility]

Ferreiro I, Genevois C, Konate K, Vivès E, Boisguérin P, Deshayes S, Couillaud F. In Vivo Follow-Up of Gene Inhibition in Solid Tumors Using Peptide-Based Nanoparticles for siRNA Delivery. Pharmaceutics. 2021 May 19;13(5):749. [PubMed] [Vivoptic]

Nguyen TL, Nokin MJ, Terés S, Tomé M, Bodineau C, Galmar O, Pasquet JM, Rousseau B, van Liempd S, Falcon-Perez JM, Richard E, Muzotte E, Rezvani HR, Priault M, Bouchecareilh M, Redonnet-Vernhet I, Calvo J, Uzan B, Pflumio F, Fuentes P, Toribio ML, Khatib AM, Soubeyran P, Murdoch PDS, Durán RV. Downregulation of Glutamine Synthetase, not glutaminolysis, is responsible for glutamine addiction in Notch1-driven acute lymphoblastic leukemia. Mol Oncol. 2021 May;15(5):1412-1431. [PubMed] [FACSility]

Karatas E, Raymond AA, Leon C, Dupuy JW, Di-Tommaso S, Senant N, Collardeau-Frachon S, Ruiz M, Lachaux A, Saltel F, Bouchecareilh M. Hepatocyte proteomes reveal the role of protein disulfide isomerase 4 in alpha 1-antitrypsin deficiency. JHEP Rep. 2021 Apr 24;3(4):100297. [PubMed] [OncoProt] [Histopathologie]

Rodriguez L, Duchez P, Touya N, Debeissat C, Guitart AV, Pasquet JM, Vlaski-Lafarge M, Brunet de la Grange P, Ivanovic Z. α-Tocopherol Attenuates Oxidative Phosphorylation of CD34+ Cells, Enhances Their G0 Phase Fraction and Promotes Hematopoietic Stem and Primitive Progenitor Cell Maintenance. Biomolecules. 2021 Apr 10;11(4):558. [PubMed] [FACSility] [Vect’UB]

Bahri H, Buratto J, Rojo M, Dompierre JP, Salin B, Blancard C, Cuvellier S, Rose M, Ben Ammar Elgaaied A, Tetaud E, di Rago JP, Devin A, Duvezin-Caubet S. TMEM70 forms oligomeric scaffolds within mitochondrial cristae promoting in situ assembly of mammalian ATP synthase proton channel. Biochim Biophys Acta Mol Cell Res. 2021 Apr;1868(4):118942. [PubMed] [Vect’UB] [FACSility]

Guyon J, Chapouly C, Andrique L, Bikfalvi A, Daubon T. The Normal and Brain Tumor Vasculature: Morphological and Functional Characteristics and Therapeutic Targeting. Front Physiol. 2021 Mar 5;12:622615. [PubMed] [VoxCell]

He W, Azzi-Martin L, Velasco V, Lehours P, Dubus P, Djavaheri-Mergny M, Ménard A. The CDT of Helicobacter hepaticus induces pro-survival autophagy and nucleoplasmic reticulum formation concentrating the RNA binding proteins UNR/CSDE1 and P62/SQSTM1. PLoS Pathog. 2021 Mar 4;17(3):e1009320. [PubMed] [CRISP’edit]

Lapaillerie D, Charlier C, Fernandes HS, Sousa SF, Lesbats P, Weigel P, Favereaux A, Guyonnet-Duperat V, Parissi V. In Silico, In Vitro and In Cellulo Models for Monitoring SARS-CoV-2 Spike/Human ACE2 Complex, Viral Entry and Cell Fusion. Viruses. 2021 Feb 25;13(3):365. [PubMed] [Vect’UB]

Kaminski H, Ménard C, El Hayani B, Adjibabi AN, Marsères G, Courant M, Zouine A, Pitard V, Garrigue I, Burrel S, Moreau JF, Couzi L, Visentin J, Merville P, Déchanet-Merville J. Characterization of a Unique γδ T-Cell Subset as a Specific Marker of Cytomegalovirus Infection Severity. J Infect Dis. 2021 Feb 24;223(4):655-666. [PubMed] [FACSility]

Moisan F, Oucherif S, Kaulanjan-Checkmodine P, Prey S, Rousseau B, Bonneu M, Claverol S, Gontier E, Lacomme S, Dousset L, Couffinhal T, Toutain J, Loot M, Cario-André M, Jullié ML, Léauté-Labrèze C, Taieb A, Rezvani HR. Critical role of Aquaporin-1 and telocytes in infantile hemangioma response to propranolol beta blockade. Proc Natl Acad Sci U S A. 2021 Feb 16;118(7):e2018690118. [PubMed] [Vect’UB]

Blouin JM, Ged C, Bernardo-Seisdedos G, Cabantous T, Pinson B, Poli A, Puy H, Millet O, Gouya L, Morice-Picard F, Richard E. Identification of novel UROS mutations in a patient with congenital erythropoietic porphyria and efficient treatment by phlebotomy. Mol Genet Metab Rep. 2021 Feb 11;27:100722. [PubMed] [SAM]

Amoedo ND, Sarlak S, Obre E, Esteves P, Bégueret H, Kieffer Y, Rousseau B, Dupis A, Izotte J, Bellance N, Dard L, Redonnet-Vernhet I, Punzi G, Rodrigues MF, Dumon E, Mafhouf W, Guyonnet-Dupérat V, Gales L, Palama T, Bellvert F, Dugot-Senan N, Claverol S, Baste JM, Lacombe D, Rezvani HR, Pierri CL, Mechta-Grigoriou F, Thumerel M, Rossignol R. Targeting the mitochondrial trifunctional protein restrains tumor growth in oxidative lung carcinomas. J Clin Invest. 2021 Jan 4;131(1):e133081. [PubMed] [Vect’UB] [Histopathologie]

 2020

Bouvet F, Ros M, Bonedeau E, Croissant C, Frelin L, Saltel F, Moreau V, Bouter A. Defective membrane repair machinery impairs survival of invasive cancer cells. Sci Rep. 2020 Dec 11;10(1):21821. [PubMed] [Vect’UB]

Mombled M, Rodriguez L, Avalon M, Duchez P, Vlaski-Lafarge M, Debeissat C, Pérard B, Sawai KM, Pasquet JM, Bijou F, Thévenot F, Cabantous T, Ivanovic Z, Brunet de la Grange P. Characteristics of cells with engraftment capacity within CD34+ cell population upon G-CSF and Plerixafor mobilization. Leukemia. 2020 Dec;34(12):3370-3381. [PubMed] [FACSility] [OneCell]

Congras A, Hoareau-Aveilla C, Caillet N, Tosolini M, Villarese P, Cieslak A, Rodriguez L, Asnafi V, Macintyre E, Egger G, Brousset P, Lamant L, Meggetto F. ALK-transformed mature T lymphocytes restore early thymus progenitor features. J Clin Invest. 2020 Dec 1;130(12):6395-6408. [PubMed] [Vect’UB]

Madore C, Leyrolle Q, Morel L, Rossitto M, Greenhalgh AD, Delpech JC, Martinat M, Bosch-Bouju C, Bourel J, Rani B, Lacabanne C, Thomazeau A, Hopperton KE, Beccari S, Sere A, Aubert A, De Smedt-Peyrusse V, Lecours C, Bisht K, Fourgeaud L, Gregoire S, Bretillon L, Acar N, Grant NJ, Badaut J, Gressens P, Sierra A, Butovsky O, Tremblay ME, Bazinet RP, Joffre C, Nadjar A, Layé S. Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain. Nat Commun. 2020 Nov 30;11(1):6133. [PubMed] [FACSility]

Leleu D, Levionnois E, Laurent P, Lazaro E, Richez C, Duffau P, Blanco P, Sisirak V, Contin-Bordes C, Truchetet ME. Elevated Circulatory Levels of Microparticles Are Associated to Lung Fibrosis and Vasculopathy During Systemic Sclerosis. Front Immunol. 2020 Oct 23;11:532177. [PubMed] [FACSility] [OneCell]

Larochette N, El-Hafci H, Potier E, Setterblad N, Bensidhoum M, Petite H, Logeart-Avramoglou D. Osteogenic-differentiated mesenchymal stem cell-secreted extracellular matrix as a bone morphogenetic protein-2 delivery system for ectopic bone formation. Acta Biomater. 2020 Oct 15;116:186-200. [PubMed] [Vect’UB]

Isaure MP, Albertelli M, Kieffer I, Tucoulou R, Petrel M, Gontier E, Tessier E, Monperrus M, Goñi-Urriza M. Relationship Between Hg Speciation and Hg Methylation/Demethylation Processes in the Sulfate-Reducing Bacterium Pseudodesulfovibrio hydrargyri: Evidences From HERFD-XANES and Nano-XRF. Front Microbiol. 2020 Oct 14;11:584715. [PubMed] [FACSility]

Velázquez D, Albacar M, Zhang C, Calafí C, López-Malo M, Torres-Torronteras J, Martí R, Kovalchuk SI, Pinson B, Jensen ON, Daignan-Fornier B, Casamayor A, Ariño J. Yeast Ppz1 protein phosphatase toxicity involves the alteration of multiple cellular targets. Sci Rep. 2020 Sep 24;10(1):15613. [PubMed] [SAM]

Prat F, Toutain J, Boutin J, Amintas S, Cullot G, Lalanne M, Lamrissi-Garcia I, Moranvillier I, Richard E, Blouin JM, Dabernat S, Moreau-Gaudry F, Bedel A. Mutation-Specific Guide RNA for Compound Heterozygous Porphyria On-target Scarless Correction by CRISPR/Cas9 in Stem Cells. Stem Cell Reports. 2020 Sep 8;15(3):677-693. [PubMed] [FACSility]

Croissant C, Gounou C, Bouvet F, Tan S, Bouter A. Annexin-A6 in Membrane Repair of Human Skeletal Muscle Cell: A Role in the Cap Subdomain. Cells. 2020 Jul 21;9(7):1742. [PubMed] [Vect’UB]

Cario M, Pain C, Kaulanjan-Checkmodine P, Masia D, Delia G, Casoli V, Costet P, Goussot JF, Guyonnet-Duperat V, Bibeyran A, Ezzedine K, Reymermier C, Andre-Frei V, Taieb A. Epidermal keratin 5 expression and distribution is under dermal influence. Pigment Cell Melanoma Res. 2020 May;33(3):435-445. [PubMed] [Vect’UB]

Soulet F, Bodineau C, Hooks KB, Descarpentrie J, Alves I, Dubreuil M, Mouchard A, Eugenie M, Hoepffner JL, López JJ, Rosado JA, Soubeyran I, Tomé M, Durán RV, Nikolski M, Villoutreix BO, Evrard S, Siegfried G, Khatib AM. ELA/APELA precursor cleaved by furin displays tumor suppressor function in renal cell carcinoma through mTORC1 activation. JCI Insight. 2020 Jul 23;5(14):e129070.[PubMed] [Vect’UB]

Capdevielle C, Desplat A, Charpentier J, Sagliocco F, Thiebaud P, Thézé N, Fédou S, Hooks KB, Silvestri R, Guyonnet-Duperat V, Petrel M, Raymond AA, Dupuy JW, Grosset CF, Hagedorn M. HDAC inhibition induces expression of scaffolding proteins critical for tumor progression in pediatric glioma: focus on EBP50 and IRSp53. Neuro Oncol. 2020 Apr 15;22(4):550-562. [PubMed] [OncoProt] [Vect’UB] [FACSility]

Sala M, Gonzales D, Leste-Lasserre T, Dugot-Senant N, Paradis V, Di Tommaso S, Dupuy JW, Pitard V, Dourthe C, Sciarra A, Sempoux C, Ferrell LD, Clouston AD, Miller G, Yeh MM, Thung S, Gouw ASH, Quaglia A, Han J, Huan J, Fan C, Crawford J, Nakanuma Y, Harada K, le Bail B, Castain C, Frulio N, Trillaud H, Possenti L, Blanc JF, Chiche L, Laurent C, Balabaud C, Bioulac-Sage P, Raymond AA, Saltel F. ASS1 Overexpression: A Hallmark of Sonic Hedgehog Hepatocellular Adenomas; Recommendations for Clinical Practice. Hepatol Commun. 2020 Apr 11;4(6):809-824. [PubMed] [OncoProt] [Histopathologie]

Karunakaran MM, Willcox CR, Salim M, Paletta D, Fichtner AS, Noll A, Starick L, Nöhren A, Begley CR, Berwick KA, Chaleil RAG, Pitard V, Déchanet-Merville J, Bates PA, Kimmel B, Knowles TJ, Kunzmann V, Walter L, Jeeves M, Mohammed F, Willcox BE, Herrmann T. Butyrophilin-2A1 Directly Binds Germline-Encoded Regions of the Vγ9Vδ2 TCR and Is Essential for Phosphoantigen Sensing. Immunity. 2020 Mar 17;52(3):487-498.e6. [PubMed] [FACSility]

Péré-Védrenne C, He W, Azzi-Martin L, Prouzet-Mauléon V, Buissonnière A, Cardinaud B, Lehours P, Mégraud F, Grosset CF, Ménard A. The Nuclear Remodeling Induced by Helicobacter Cytolethal Distending Toxin Involves MAFB Oncoprotein. Toxins (Basel). 2020 Mar 12;12(3):174. [PubMed] [CRISP’edit] [Vect’UB] [Histopathologie]

Prévot G, Bsaibess T, Daniel J, Genevois C, Clermont G, Sasaki I, Marais S, Couillaud F, Crauste-Manciet S, Blanchard-Desce M. Multimodal optical contrast agents as new tools for monitoring and tuning nanoemulsion internalisation into cancer cells. From live cell imaging to in vivo imaging of tumours. Nanoscale Adv. 2020 Feb 27;2(4):1590-1602. [PubMed] [Vivoptic]

Massara L, Khairallah C, Yared N, Pitard V, Rousseau B, Izotte J, Giese A, Dubus P, Gauthereau X, Déchanet-Merville J, Capone M. Uncovering the Anticancer Potential of Murine Cytomegalovirus against Human Colon Cancer Cells. Mol Ther Oncolytics. 2020 Jan 29;16:250-261. [PubMed] [FACSility] [OneCell]

Auguste P, Leitinger B, Liard C, Rocher V, Azema L, Saltel F, Santamaria D. Meeting report – first discoidin domain receptors meeting. J Cell Sci. 2020 Feb 24;133(4):jcs243824. [PubMed] [OncoProt]

Ghousein A, Mosca N, Cartier F, Charpentier J, Dupuy JW, Raymond AA, Bioulac-Sage P, Grosset CF. miR-4510 blocks hepatocellular carcinoma development through RAF1 targeting and RAS/RAF/MEK/ERK signalling inactivation. Liver Int. 2020 Jan;40(1):240-251. [PubMed] [Vect’UB] [FACSility] [Histopathologie]

 2019

González A, Casado J, Chueca E, Salillas S, Velázquez-Campoy A, Espinosa Angarica V, Bénejat L, Guignard J, Giese A, Sancho J, Lehours P, Lanas Á. Repurposing Dihydropyridines for Treatment of Helicobacter pylori Infection. Pharmaceutics. 2019 Dec 15;11(12):681. [PubMed] [OneCell]

Mansier O, Prouzet-Mauléon V, Jégou G, Barroso K, Raymundo DP, Chauveau A, Dumas PY, Lagarde V, Turcq B, Pasquet JM, Viallard JF, James C, Praloran V, Voutetakis K, Chatziioannou A, Mahon FX, Chevet E, Lippert E. The Expression of Myeloproliferative Neoplasm-Associated Calreticulin Variants Depends on the Functionality of ER-Associated Degradation. Cancers (Basel). 2019 Dec 2;11(12):1921. [PubMed] [FACSility]

Blumenstock S, Angelo MF, Peters F, Dorostkar MM, Ruf VC, Luckner M, Crux S, Slapakova L, Arzberger T, Claverol S, Herzog E, Herms J. Early defects in translation elongation factor 1α levels at excitatory synapses in α-synucleinopathy. Acta Neuropathol. 2019 Dec;138(6):971-986. [PubMed] [FACSility]

Tomé M, Pappalardo A, Soulet F, López JJ, Olaizola J, Leger Y, Dubreuil M, Mouchard A, Fessart D, Delom F, Pitard V, Bechade D, Fonck M, Rosado JA, Ghiringhelli F, Déchanet-Merville J, Soubeyran I, Siegfried G, Evrard S, Khatib AM. Inactivation of Proprotein Convertases in T Cells Inhibits PD-1 Expression and Creates a Favorable Immune Microenvironment in Colorectal Cancer. Cancer Res. 2019 Oct 1;79(19):5008-5021. [PubMed] [FACSility]

Daubon T, Guyon J, Raymond AA, Dartigues B, Rudewicz J, Ezzoukhry Z, Dupuy JW, Herbert JMJ, Saltel F, Bjerkvig R, Nikolski M, Bikfalvi A. The invasive proteome of glioblastoma revealed by laser-capture microdissection. Neurooncol Adv. 2019 Sep 28;1(1):vdz029. [PubMed] [OncoProt]

Hafner AS, Donlin-Asp PG, Leitch B, Herzog E, Schuman EM. Local protein synthesis is a ubiquitous feature of neuronal pre- and postsynaptic compartments. Science. 2019 May 17;364(6441):eaau3644. [PubMed] [FACSility]

Dumas PY, Naudin C, Martin-Lannerée S, Izac B, Casetti L, Mansier O, Rousseau B, Artus A, Dufossée M, Giese A, Dubus P, Pigneux A, Praloran V, Bidet A, Villacreces A, Guitart A, Milpied N, Kosmider O, Vigon I, Desplat V, Dusanter-Fourt I, Pasquet JM. Hematopoietic niche drives FLT3-ITD acute myeloid leukemia resistance to quizartinib via STAT5-and hypoxia-dependent upregulation of AXL. Haematologica. 2019 Oct;104(10):2017-2027. [PubMed] [FACSility] [Vect’UB] [Histopathologie]

Gerbod-Giannone MC, Dallet L, Naudin G, Sahin A, Decossas M, Poussard S, Lambert O. Involvement of caveolin-1 and CD36 in native LDL endocytosis by endothelial cells. Biochim Biophys Acta Gen Subj. 2019 May;1863(5):830-838. [PubMed] [FACSility]

Vial G, Rivière E, Raymond AA, James C, Di-Tommaso S, Dugot-Senant N, Dupuy JW, Yacoub M, Parrens M, Saltel F, Viallard JF. Antigenic Mimicry in Paraneoplastic Immune Thrombocytopenia. Front Immunol. 2019 Mar 22;10:523. [PubMed] [OncoProt] [Histopathologie]

Cullot G, Boutin J, Toutain J, Prat F, Pennamen P, Rooryck C, Teichmann M, Rousseau E, Lamrissi-Garcia I, Guyonnet-Duperat V, Bibeyran A, Lalanne M, Prouzet-Mauléon V, Turcq B, Ged C, Blouin JM, Richard E, Dabernat S, Moreau-Gaudry F, Bedel A. CRISPR-Cas9 genome editing induces megabase-scale chromosomal truncations. Nat Commun. 2019 Mar 8;10(1):1136. [PubMed] [Vect’UB]

 2018

Jacquemin C, Augusto JF, Scherlinger M, Gensous N, Forcade E, Douchet I, Levionnois E, Richez C, Lazaro E, Duffau P, Truchetet ME, Seneschal J, Couzi L, Pellegrin JL, Viallard JF, Schaeverbeke T, Pascual V, Contin-Bordes C, Blanco P. OX40L/OX40 axis impairs follicular and natural Treg function in human SLE. JCI Insight. 2018 Dec 20;3(24):e122167. [PubMed] [FACSility]

Lapostolle V, Chevaleyre J, Duchez P, Rodriguez L, Vlaski-Lafarge M, Sandvig I, Brunet de la Grange P, Ivanovic Z. Repopulating hematopoietic stem cells from steady-state blood before and after ex vivo culture are enriched in the CD34+CD133+CXCR4low fraction. Haematologica. 2018 Oct;103(10):1604-1615. [PubMed] [FACSility]

Latour S, Mahouche I, Cherrier F, Azzi-Martin L, Velasco V, Soubeyran P, Merlio JP, Poglio S, Bresson-Bepoldin L. Calcium Independent Effect of Orai1 and STIM1 in Non-Hodgkin B Cell Lymphoma Dissemination. Cancers (Basel). 2018 Oct 26;10(11):402. [PubMed] [FACSility]

Labrousse VF, Leyrolle Q, Amadieu C, Aubert A, Sere A, Coutureau E, Grégoire S, Bretillon L, Pallet V, Gressens P, Joffre C, Nadjar A, Layé S. Dietary omega-3 deficiency exacerbates inflammation and reveals spatial memory deficits in mice exposed to lipopolysaccharide during gestation. Brain Behav Immun. 2018 Oct;73:427-440. [PubMed] [FACSility]

Nguyen TL, Nokin MJ, Egorov M, Tomé M, Bodineau C, Di Primo C, Minder L, Wdzieczak-Bakala J, Garcia-Alvarez MC, Bignon J, Thoison O, Delpech B, Surpateanu G, Frapart YM, Peyrot F, Abbas K, Terés S, Evrard S, Khatib AM, Soubeyran P, Iorga BI, Durán RV, Collin P. mTOR Inhibition via Displacement of Phosphatidic Acid Induces Enhanced Cytotoxicity Specifically in Cancer Cells. Cancer Res. 2018 Sep 15;78(18):5384-5397. [PubMed] [FACSility]

Leitinger B, Saltel F. Discoidin domain receptors: multitaskers for physiological and pathological processes. Cell Adh Migr. 2018;12(4):398-399. [PubMed] [OncoProt]

Hooks KB, Audoux J, Fazli H, Lesjean S, Ernault T, Dugot-Senant N, Leste-Lasserre T, Hagedorn M, Rousseau B, Danet C, Branchereau S, Brugières L, Taque S, Guettier C, Fabre M, Rullier A, Buendia MA, Commes T, Grosset CF, Raymond AA. New insights into diagnosis and therapeutic options for proliferative hepatoblastoma. Hepatology. 2018 Jul;68(1):89-102. [PubMed] [Histopathologie]

Ezzoukhry Z, Henriet E, Cordelières FP, Dupuy JW, Maître M, Gay N, Di-Tommaso S, Mercier L, Goetz JG, Peter M, Bard F, Moreau V, Raymond AA, Saltel F. Combining laser capture microdissection and proteomics reveals an active translation machinery controlling invadosome formation. Nat Commun. 2018 May 23;9(1):2031. [PubMed] [OncoProt] [Histopathologie]

Indersie E, Hooks KB, Capdevielle C, Fabre M, Dugot-Senant N, Desplat A, Lepreux S, Merched A, Grosset CF, Hagedorn M. Tracking cellular and molecular changes in a species-specific manner during experimental tumor progression in vivo. Oncotarget. 2018 Mar 1;9(22):16149-16162. [PubMed] [Histopathologie]

Dallet L, Decossas M, Taveau JC, Lecomte S, Poussard S, Lambert O, Pitard B. Single lipoaminoglycoside promotes efficient intracellular antibody delivery: A comprehensive insight into the mechanism of action. Nanomedicine. 2018 Jan;14(1):141-151. [PubMed] [FACSility]

2017

Henriet E, Abou Hammoud A, Dupuy JW, Dartigues B, Ezzoukry Z, Dugot-Senant N, Leste-Lasserre T, Pallares-Lupon N, Nikolski M, Le Bail B, Blanc JF, Balabaud C, Bioulac-Sage P, Raymond AA, Saltel F. Argininosuccinate synthase 1 (ASS1): A marker of unclassified hepatocellular adenoma and high bleeding risk. Hepatology. 2017 Dec;66(6):2016-2028. [PubMed] [OncoProt] [Histopathologie]

Floch P, Izotte J, Guillemaud J, Sifré E, Costet P, Rousseau B, Laur AM, Giese A, Korolik V, Mégraud F, Dubus P, Hahne M, Lehours P. A New Animal Model of Gastric Lymphomagenesis: APRIL Transgenic Mice Infected by Helicobacter Species. Am J Pathol. 2017 Jul;187(7):1473-1484. [PubMed] [OneCell] [Histopathologie]

Ianniciello A, Dumas PY, Drullion C, Guitart A, Villacreces A, Peytour Y, Chevaleyre J, Brunet de la Grange P, Vigon I, Desplat V, Priault M, Sbarba PD, Ivanovic Z, Mahon FX, Pasquet JM. Chronic myeloid leukemia progenitor cells require autophagy when leaving hypoxia-induced quiescence. Oncotarget. 2017 Jun 30;8(57):96984-96992. [PubMed] [Vect’UB]

Cartier F, Indersie E, Lesjean S, Charpentier J, Hooks KB, Ghousein A, Desplat A, Dugot-Senant N, Trézéguet V, Sagliocco F, Hagedorn M, Grosset CF. New tumor suppressor microRNAs target glypican-3 in human liver cancer. Oncotarget. 2017 Jun 20;8(25):41211-41226. [PubMed] [Histopathologie]

Saltel F, Giese A, Azzi L, Elatmani H, Costet P, Ezzoukhry Z, Dugot-Senant N, Miquerol L, Boussadia O, Wodrich H, Dubus P, Jacquemin-Sablon H. Unr defines a novel class of nucleoplasmic reticulum involved in mRNA translation. J Cell Sci. 2017 May 15;130(10):1796-1808. [PubMed] [Histopathologie]

Ventura M, Martin L, Jaubert C, Andréola ML, Masante C. Hepatitis C virus intragenomic interactions are modulated by the SLVI RNA structure of the core coding sequence. J Gen Virol. 2017 Apr;98(4):633-642. [PubMed] [FACSility]

Bourdieu A, Avalon M, Lapostolle V, Ismail S, Mombled M, Debeissat C, Guérinet M, Duchez P, Chevaleyre J, Vlaski-Lafarge M, Villacreces A, Praloran V, Ivanovic Z, Brunet de la Grange P. Steady state peripheral blood provides cells with functional and metabolic characteristics of real hematopoietic stem cells. J Cell Physiol. 2018 Jan;233(1):338-349. [PubMed] [FACSility]

Marlin R, Pappalardo A, Kaminski H, Willcox CR, Pitard V, Netzer S, Khairallah C, Lomenech AM, Harly C, Bonneville M, Moreau JF, Scotet E, Willcox BE, Faustin B, Déchanet-Merville J. Sensing of cell stress by human γδ TCR-dependent recognition of annexin A2. Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):3163-3168. [PubMed] [Vect’UB]

2016

Mélard P, Idrissi Y, Andrique L, Poglio S, Prochazkova-Carlotti M, Berhouet S, Boucher C, Laharanne E, Chevret E, Pham-Ledard A, De Souza Góes AC, Guyonnet-Duperat V, Bibeyran A, Moreau-Gaudry F, Vergier B, Beylot-Barry M, Merlio JP, Cappellen D. Molecular alterations and tumor suppressive function of the DUSP22 (Dual Specificity Phosphatase 22) gene in peripheral T-cell lymphoma subtypes. Oncotarget. 2016 Oct 18;7(42):68734-68748. [PubMed] [Vect’UB]

Fessart D, Domblides C, Avril T, Eriksson LA, Begueret H, Pineau R, Malrieux C, Dugot-Senant N, Lucchesi C, Chevet E, Delom F. Secretion of protein disulphide isomerase AGR2 confers tumorigenic properties. Elife. 2016 May 30;5:e13887. [PubMed] [Histopathologie]

Mazzocco C, Fracasso G, Germain-Genevois C, Dugot-Senant N, Figini M, Colombatti M, Grenier N, Couillaud F. In vivo imaging of prostate cancer using an anti-PSMA scFv fragment as a probe. Sci Rep. 2016 Mar 21;6:23314. [PubMed] [Histopathologie]

2015

Laur AM, Floch P, Chambonnier L, Benejat L, Korolik V, Giese A, Dubus P, Mégraud F, Bandeira A, Lehours P. Regulatory T cells may participate in Helicobacter pylori persistence in gastric MALT lymphoma: lessons from an animal model. Oncotarget. 2016 Jan 19;7(3):3394-402. [PubMed] [OneCell]

Floch P, Laur AM, Korolik V, Chrisment D, Cappellen D, Idrissi Y, Dubus P, Mégraud F, Lehours P. Characterisation of inflammatory processes in Helicobacter pylori-induced gastric lymphomagenesis in a mouse model. Oncotarget. 2015 Oct 27;6(33):34525-36. [PubMed] [OneCell]